We reported two patients with nasopharyngeal adenocarcinoma resected by using the exclusively endoscopic approach. Case reports and a review of the world literature concerning nasopharyngeal adenocarcinoma. The tumors were resected successfully via the exclusively endoscopic approach and no conversions to the conventional approach were necessary. The two patients were followed up for 26 and 18 ...

PURPOSE Nasopharyngeal carcinoma (NPC) is a common cancer in southern China and Southeast Asia, but risk stratification and treatment outcome in NPC patients remain suboptimal. Our study identified and validated metabolic drivers that are relevant to the pathogenesis of NPC using a published transcriptome. Phosphoserine aminotransferase 1 (PSAT1) is an enzyme that is involved in serine biosynth...

Rectal cancer carries poor prognosis because of metastasis and local recurrence. Local recurrence has a profound effect on morbidity and quality of life. Therefore, preoperative staging of rectal cancer has an important impact on treatment plan. The main factor in predicting the local recurrence is the circumferential resection margin (CRM). Surgical resection with stage-appropriate neoadjuvant...

Types and treatment of breast cancer recurrence Recurrence describes the return of breast cancer after primary treatment.1 There are three types of recurrent breast cancer:1 • Local recurrence occurs when cancerous cells reappear at the original tumour site over time. Local breast cancer recurrence is not considered to be a spread of the cancer but rather due to failure of the initial treatment...

BACKGROUND The routine application of neoadjuvant chemoradiotherapy for T3N0 rectal cancer remains controversial. The aim of this study was to use clinical, Magnetic resonance imaging, and pathological parameters to identify a subgroup of patients with low risk of local recurrence who might be precluded from neoadjuvant chemoradiotherapy. METHODS We retrospectively reviewed a prospectively ma...

BACKGROUND The purpose of this study was to explore the significance of resection margin status on local recurrence and survival for early (T1/T2) oral cancer and to determine if the significance of the resection margin varies with the biological aggression of the tumor as determined by pN status. METHODS The influence of resection margin size and local recurrence for 295 patients with pT1/T2...

although splenic metastasis is fairly common in disseminated cancer, solitary splenic metastasis in the absence of diffuse dissemination is rare. we report a case of 44 year-old man who developed isolated splenic metastasis of colon cancer. the patient had undergone right sided hemicolectomy for colon cancer in 1988. in 2001, he underwent reoperation because of local recurrence of tumor in the ...