AIM OF THE STUDY To assess the tolerability, toxicity and efficacy of neo-adjuvant Docetaxel and Cisplatin (TC) followed by concurrent Cisplatin and radiotherapy (RT) in patients with loco-regionally advanced nasopharyngeal carcinoma (NPC). PATIENTS AND METHODS Fourteen patients with locally advanced NPC received two cycles of Docetaxel (75 mg/m2 on days 1, and 21) and Cisplatin (75 mg/m2 on ...

Traditional open approaches to the nasopharynx either provide limited access and risk significant morbidity. Here we describe our experience with endoscopic resection of nasopharyngeal tumours. Retrospective chart review was performed for all patients who underwent endoscopic nasopharyngeal resection from September 1993 to January 2007 at a tertiary rhinology centre. Six patients underwent endo...

Melanotic oncocytic metaplasia (MOM) of the nasopharynx is an extremely rare benign lesion which characterized by presence usually a small, pigmented near Eustachian tube opening, but never reported form cyst without pigmentation. A 76-year-old man who had symptom with globus pharyngeus for 3 months was presented to otolaryngology clinic. The found as cystic mass pigmentation through endoscopic...

BACKGROUND AND PURPOSE The development of a new polyp or mass in the radiation field of a previously treated carcinoma is usually an ominous sign of a recurrent cancer, but rarely may it be caused instead by a nonmalignant process. The purpose of this study was to document the MR appearance of unusual nonmalignant polyps or masses (NMPMs) in the nasopharynx and sphenoid sinus arising after radi...

INTRODUCTION Nasopharyngectomy has been established as a feasible curative treatment for salvaging recurrent nasopharyngeal carcinoma after radical radiotherapy. A large case series has also shown that the overall survival rate in nasopharyngectomy is comparable with reirradiation in small recurrent tumors. However, reirradiation has significant late complications from radiotherapy, and surgica...

Nasopharyngeal carcinoma (NPC) is an EBV-associated malignant tumor of nasopharynx. As extremely rare condition, the second primary cancer of nasopharynx can occur in NPC patients synchronously or subsequently. Extramedullary plasmacytoma (EMP) is a rare tumor and commonly originates in the head and neck region. However, there is no report to describe a collision tumor of NPC and EMP occurring ...

The mammalian pharynx is a hollow muscular tube that participates in ingestion and respiration, and its size, shape, and stiffness can be altered by contraction of skeletal muscles that lie inside or outside of its walls. MRI was used to determine the interaction between pharyngeal pressure and selective stimulation of extrinsic tongue muscles on the shape of the rat nasopharynx. Pressure (-9, ...

BACKGROUND Reverse-transcriptase quantitative real-time polymerase chain reaction (RT-qPCR) has become the gold standard for the diagnosis of human enterovirus (EV) and parechovirus (HPeV) infections. The detection rate of RT-qPCR in different pediatric body specimens has not been compared prospectively in a multicentre study. OBJECTIVES This study compared the diagnostic detection rates of E...

BACKGROUND The purpose of this study was to investigate the treatment outcome of radiation-induced squamous cell carcinoma (SCC) of the nasopharynx after radiotherapy (RT) for nasopharyngeal carcinoma (NPC). METHODS We conducted a retrospective review of patients who underwent radiation therapy for NPC, which resulted in radiation-induced SCC of the nasopharynx. RESULTS Between 1998 and 201...