We examined plasma levels of the sympathetic neurotransmitter norepinephrine (NE) and its deaminated metabolite dihydroxyphenylglycol (DHPG) during supine rest in healthy human subjects and in sympathectomized patients, during physiological (tilt) or pharmacological (yohimbine, clonidine) manipulations known to affect sympathetically mediated NE release, during blockade of neuronal uptake of NE...

Department of Environmental, Agricultural and Occupational Health, University of Nebraska Medical Center, Omaha, NE Nebraska Biocontainment Unit, Nebraska Medicine, Omaha, NE Department of Internal Medicine, University of Nebraska Medical Center, Omaha, NE d Trauma and Preparedness Services, Nebraska Medicine, Omaha, NE Department of Pathology and Microbiology, University of Nebraska Medical Ce...

We have measured helium and neon concentrations, elemental and isotopic ratios of 91 individual presolar graphite grains from the KFC1 density separate of the Murchison meteorite. Eleven grains contain measurable amounts of either He, Ne, Ne or Ne, or a combination thereof. We report the first detection of Ne from an individual presolar graphite grain and the first detection of He and Ne in ind...

Obstructive sleep apnea (OSA) is characterized by noradrenergic activation. Nasal continuous positive airway pressure (CPAP) is the treatment of choice and has been shown to effectively reduce elevated norepinephrine (NE) levels. This study examined whether the reduction in NE after CPAP is due to an increase in NE clearance and/or a decrease of NE release rate. Fifty CPAP-naive OSA patients wi...

Understanding the connection between sympathetic activity and essential hypertension is still rudimentary. We studied interrelationships of plasma catecholamines, plasma renin activity (PRA), aldosterone, sodium intake, and therapeutic response of 20 normal renin hypertensives. Based on plasma norepinephrine (NE), this population fell into two distinct subsets. The 11 patients in the "normal" N...

We reported recently that inhibition of neuronal reuptake of norepinephrine (NE) by desipramine prevented the reduction of sympathetic neurotransmitters in the failing right ventricle of right heart failure animals. In this study, we studied whether desipramine also reduced the sympathetic neurotransmitter loss in animals with left heart failure induced by rapid ventricular pacing (225 beats/mi...

OBJECTIVE To assess whether cardiac failure, because of cardiac defects, and abnormal jugular lymphatic development are involved in nuchal edema (NE) - the morphological equivalent of increased nuchal translucency - in various euploid mutant mouse models. METHOD Mouse embryos with lymphatic abnormalities and NE (Ccbe1(-/-)), with cardiac defects and NE (Fkbp12(-/-), Tbx1(-/-), Chd7(fl/fl);Mes...

Nuruk contributes to the unique characteristics of Korean alcoholic beverages. In this study, the effects of nuruk extracts (NE) on anti-oxidant characters, melanogenesis, and anti-photoaging activity were investigated. NEs were obtained from the 70% ethanol extracts of six types of nuruk, which have been used in brewing of fermented alcohol beverages in Korea. First, various antioxidant charac...

OBJECTIVE This experiment investigated the effect of dietary net energy (NE) concentrations on growth performance and NE intake of growing gilts. METHODS Five diets were formulated to contain 9.6, 10.1, 10.6, 11.1, and 11.6 MJ NE/kg, respectively. A metabolism trial with 10 growing pigs (average body weight [BW] = 15.9±0.24 kg) was conducted to determine NE concentrations of 5 diets based on ...

This paper presents a new bootstrapping approach to named entity (NE) classification. This approach only requires a few common noun/pronoun seeds that correspond to the concept for the target NE type, e.g. he/she/man/woman for PERSON NE. The entire bootstrapping procedure is implemented as training two successive learners: (i) a decision list is used to learn the parsing-based high precision NE...