BACKGROUND Respiratory disease accounts for three of the ten leading causes of death worldwide. Many of these diseases can be treated and diagnosed using a nebulizer. Nebulizers can also be used to safely and efficiently deliver vaccines. Unfortunately, commercially available nebulizers are not designed for use in regions of the world where lung disease is most prevalent: they are electricity-d...

Inhalation is a very old method of drug delivery, and in the 20th century it became a mainstay of respiratory care, known as aerosol therapy. Use of inhaled epinephrine for relief of asthma was reported as early as 1929, in England. An early version of a dry powder inhaler (DPI) was the Aerohalor, used to administer penicillin dust to treat respiratory infections. In the 1950s, the Wright nebul...

BACKGROUND Aerosol therapy in preterm infants is challenging, as a very small proportion of the drug deposits in the lungs. AIM Our aim was to compare efficiency of standard devices with newer, more efficient aerosol delivery devices. METHODS Using salbutamol as a drug marker, we studied two prototypes of the investigational eFlow(®) nebulizer for babies (PARI Pharma GmbH), a jet nebulizer ...

Reproducibility and comparability of bronchial challenge tests depends critically on accurate assessment of nebulizer output. Evaporation during nebulization means that simple weighing is inaccurate, overestimating the delivered dose of active ingredient. We wanted to quantify this effect in the context of intermittent nebulization, using a dosimeter as used in bronchial provocation tests. Outp...

BACKGROUND In-line administration of bronchodilators is widely used in pediatric patients receiving mechanical ventilation. We compared the amount of albuterol captured at the end of the endotracheal tube (ETT) with an intrapulmonary percussive ventilator (IPV) versus a Salter 8900 jet nebulizer placed in-line in a pediatric ventilator model, under various operating conditions. We hypothesized ...

Nebulizer is one of inhalation therapy’s most widely used aerosol generation devices. Nowadays, the vibrating mesh nebulizer has become popular owing to its compactness and noiselessness. In this study, an experimental system proposed measure deposition fraction (DF) nebulized sodium chloride (NaCl) droplets in idealized mouth-throat airway model. The results show that before DF increases 58.6%...

ABSTRACTBackground Bronchopneumonia is a disease that attacks the respiratory tract where inflammation occurs in lungs. which affects bronchi to alveoli of lungs, bronchopneumonia with manifestations varying from coughing, runny nose, fever, accompanied by shortness breath. So it will cause ineffective airway clearance children. One nursing actions given pediatric patients nebulizer and Ventoli...