Aims Root canal treatment is a procedure that requires, beyond the realm of technique, knowledge of the internal anatomy of the root canal, specifically the anatomical apex. Almost all methodologies studied thus far are destructive, laborious, and time-consuming and allow for only one-dimensional measurements. In the present study, we used micro-CT technology to evaluate the anatomical structur...

Microbial etiology for anti-osteoclastic drug-related osteonecrosis of the jaw (ARONJ) was suggested. This study investigates any link between bacteria colonizing ARONJ sites and other oral cavity sites. Microbiota samples of 10 ARONJ patients were collected from the exposed bone, adjacent teeth, contralateral teeth, and tongue. DNA checkerboard hybridization was used for microbiota analysis wi...

OBJECTIVE The purpose of this prospective study was: 1) to follow-up a large number of endodontic treatments performed by a single operator, periodically checked over a 5-year period; and 2) to correlate outcome to a number of clinical variables. STUDY DESIGN This prospective study included all consecutive cases during the selected time period. All cases were followed regularly for a 5-year p...

AIM: The aim of this study is to evaluate the antimicrobial effect pre-synthesized novel antibiotic loaded electrospun nanofibers and compare it with conventional triple paste when used in patients immature necrotic teeth. METHODS: Antibiotic were fabricated by electrospinning. Thirty-four teeth included study. In first visit, access cavity preparation was performed obtain bacteriological sampl...

statement of problem: endodontic treatment of necrotic teeth with open apices is a challenge. after ruling out surgery as a treatment scheme and introduction of the multivisit apexification which in turn had its disadvantages, apical plug seems to be a suitable substitute treatment plan for such cases. apical plug makes the treatment through formation of a barrier against the obturating materia...

OBJECTIVE Pulp regeneration within the root canal of necrotic teeth is considered an ideal treatment to allow for continued root development and recover teeth vitality. This study aims to evaluate the inductive effect of platelet-rich plasma (PRP) on expression of angiogenesis factors and pulpal revascularization of immature necrotic teeth. MATERIALS AND METHODS In this experimental animal st...