Age-related macular degeneration (AMD) is the most common cause of blindness among the elderly, especially in Western countries. Although the prevalence, risk factors, and clinical course of the disease are well described, its pathogenesis is not entirely elucidated. AMD is associated with a variety of biochemical abnormalities, including complement components deposition in the retinal pigment ...

The inferior alveolar nerve (IAN) is a branch of the trigeminal nerve and this nerve supplies sensation to the ipsilateral lower lip, teeth, and buccal mandibular gingivae. The anatomical position of IAN places this nerve at increased injury risk. During oral surgery, the nerve tissue may be damaged so paresthesia which is characterized by the sensorineural loss that may occur [1,2]. Neurosenso...

Hearing loss and individualities Studies have shed light on the physiology of auditory system, which is fundamental to understanding diversity found in deaf community. A study by Silva discusses 3 types load described Silman & Silverman’s classification system: conductive, neurosensory, mixed. The first type caused inflammatory processes, excess cerumen external canal, changes articulation ossi...

Introduction: Central serous chorio-retinopathy is self-limited in the majority of patients, who usually retain excellent vision. However, those who do not resolve spontaneously may develop permanent visual impairment because of pigment epithelial and photoreceptor damage. Most clinicians prefer to observe these patients for three months before considering any treatment options because most cas...

Combination of chemotherapy and surgical resection of metastases is the most promising strategy to improve the fraction of long-term survivors and cured patients in metastatic colorectal cancer. We reproducibly observed evidence of exacerbation of the oxaliplatin-induced neurosensory toxicity following surgery. Total, protein-bound and intra-erythrocytic concentrations of oxaliplatin were measu...

Introduction: The most common surgical procedure performed in the oral cavity is extraction of mandibular third molar, and it has also some complications which include postoperative neurosensory deficits. incidence various deficits after lower molar removal been reported from studies countries. For example, inferior alveolar nerve (IAN) injury, manifests itself as paresthesia or complete loss s...

PURPOSE The purpose of this study was to investigate light damage-induced transcript changes within neurosensory retina (NSR) and isolated retinal pigment epithelium (RPE). Similar studies have been conducted previously, but were usually limited to the NSR and only a portion of the transcriptome. Herein most of the transcriptome, not just in the NSR but also in isolated RPE, was queried. METH...