Çalışmada Okratoksin A’nın (OTA) işaretsiz bir yöntemle tayinine yönelik elektrokimyasal aptasensör tasarımı gerçekleştirilmiştir. 5’ ucundan tiyohekzil işaretli (SH-(CH 2 ) 6 ) aptamer dizileri tek kullanımlık perde baskılı altın elektrot (AuSCPE) yüzeylerine tiyol grubu ile bağlanmıştır. OTA ve DNA aptamer dizisi arasındaki bağlanma Elektrokimyasal Empedans Spektrometri tekniği (EIS) ile 5mM ...

Oculodermal melanocytosis (ODM) is a congenital melanocytic hyperpigmentation of the face and ocular tissues. The eponym naevus of Ota as described by Otal has been used interchangeably with ODM and ocular melanosis (OM) in many reported cases. The original definition by Ota included patients with and without ocular involvement. For these reasons, we will refer to the term oculodermal melanocyt...

Naevus of Ota (naevus fusculocoeruleus ophthalmomaxillaris) was described by the Japanese dermatologist, Ota, in 1939 as a dermal melanocytic hamartoma that presents as bluish hyperpigmentation along the ophthalmic, maxillary, and mandibular branches of the trigeminal nerve. It is bilateral in less than 5% cases, occurring frequently in Orientals (0.2%–1%) and darker races and rarely in white p...

A woman with bilateral ocular melanocytosis developed a malignant melanoma of the choroid in one eye. The ocular melanotic hyperpigmentation, present since childhood, clinically involved the conjunctiva and episcleral and uveal tract of both eyes. To our knowledge this is only the second reported case of a uveal malignant melanoma in a patient with bilateral ocular melanocytosis. There is evide...

A class of RC-OTA hysteretic-chaotic generators has been proposed from the electronics point of view. Hysteresis is captured by an electronic realization. To extend its applicability, hysteretic mathematical modeling is an important issue. Here, a new hysteretic model is proposed. With this model, we realized a well known hysteretic-chaotic attractor using Simnon.

Abstract: This paper presents a new general synthesis method for high-order current mode Operational Transconductance Amplifiers and Capacitors, (OTA-C) filters. The method is based on the analytical solution of a single, nth-order generic filter transfer function and the generation of n, number of realizable transfer functions implemented using lossless integrators. The method provides systema...

Uveal melanoma is the most common primary intraocular malignancy in adults. The disease overwhelmingly affects white populations. Other risk factors include fair skin, light iris color, ancestry from northern latitudes, and ocular/oculodermal melanocytosis. Historically, enucleation was the definitive treatment of uveal melanoma, but brachytherapy and proton beam irradiation are now the most co...