Critically ill newborns, whether term or preterm, are at great risk for developing symptomatic thromboembolic disease. Comorbidities like inflammation, DIC, fluctuations in cardiac output, congenital heart disease, as well as central venous or arterial catheters, are the predisposing risk factors. Clinically symptomatic or asymptomatic cases are usually picked up by echocardiography, usually do...

Study of the structural features of the pulmonary circulation in various types of congenital heart disease makes it possible to correlate function and structure in the fetal and newborn lung. We applied quantitative morphometric techniques to the injected and inflated lungs of newborn infants who had died with obstruction to left ventricular outflow from aortic atresia, stenosis, or coarctation...

We report a case of a premature infant presenting with recurrent pulmonary hemorrhage in which we performed a therapeutic lavage with diluted surfactant after an acute episode of bleeding with severe intractable hypoxemia. Repeated small aliquots of diluted surfactant (10×2 mL) allowed rapid improvement in oxygenation and reduction of required mean airway pressures during high frequency oscilla...

The high costs of artificial pulmonary surfactants, ranging in hundreds per kilogram of body weight, used for treating the respiratory distress syndrome (RDS) premature babies have limited their applications. We have extensively studied soy lecithins and higher alcohols as lipid alternatives to expensive phospholipids such as DPPC and PG. As a substitute for the proteins, we have synthesized th...

Spectrophotofluorometricmicromethodsfor the determination of phenylalanineand tyrosine on 25 ,J. of serum are described. These methods were applied to detect phenylketonuriaamong homozygotesand heterozygotesand in the newborn population. The data presentedagreewith those previouslyreported. (1) Phenylketonurics have markedly elevated serum phenylalanineand lower serum tyrosinethan the controls....

Abstract: Intrauterine growth restriction and prematurity determine low birth weight. The combination of the three conditions results in different neonatal phenotypes that interfere with child survival. Neonatal prevalence, survival mortality were estimated according to cohort live births 2021 state Rio de Janeiro, Brazil. In this study, multiple pregnancies, congenital anomalies inconsistencie...

abstract background and objective: nutritional factors are a matter of debate in the etiology of preterm labor. this study was conducted to assess the association of maternal folic acid consumption with preterm labor .comprised and materials and methods: this cohort study was conducted on 191 healthy pregnant women in 2009, referring to two teaching hospitals in tehran (iran). the folic acid in...

objective: pulmonary air-leakage especially pneumothorax (ptx), is a severe complication in neonates. the aim of this study was to assess the predisposing factors and frequency of ptx among the low birth weight (lbw) premature infants, under mechanical ventilation. methods: this cross sectional study was performed in 121 lbw intubated premature infants at neonatal intensive care unit of a child...

OBJECTIVE To compare inflammatory mediators in the cord blood of premature newborn infants with premature rupture of membranes (PROM) and intact membranes. METHODS Eighty-nine premature neonates with gestational age of 27-34 weeks that delivered in Ghaem Hospital in Mashhad, Iran from June 2005 to March 2006 were enrolled in a prospective observational study, and their umbilical cord plasma w...

Tracheal agenesis is a rare congenital airway anomaly that usually results in a fatal outcome. The diagnosis is usually made through post-mortem examination. In the current literature, there has been no reported long-term survival although a few reports claimed prolongation of life of several hours to days. This condition is commonly associated with premature birth, polyhydramnios and a male pr...