The nitrofurazone (NF) electrochemical reduction has been studied by cyclic voltammetry (CV) and square wave (SWV) in non-aqueous medium using three different ionic liquids (IL): BMImTf2N, BMImBF4 BMMImTf2N, having a carbon fiber microelectrode as working electrode. In all of them, two reversible cathodic peaks were recorded for NF. Under higher frequency values, only one peak was registered. s...

Aqueous extract of the roots of Radix paeoniae (Paeonaceae) was screened for wound healing by excision, incision and dead space wound models on Wistar rats. The parameters studied were breaking strength in case of incision wounds, epithelialisation and wound contraction in case of excision wound and granulation tissue dry weight, breaking strength and hydroxyproline content in case of dead spac...

Pustular allergic contact dermatitis (ACD) is rare, with reactions to the topical antibacterial nitrofurazone (1), isoconazole nitrate (2), topical minoxidil 2% (3), 1% fluorouracil (4), black rubber (5) and tricholoroethylene (6) having been reported. The clinical appearance of pustular ACD has been reported to comprise multiple small pustules, only 0.5–1mm in size, on a background of erythema...

ipa-43d is a hypothetical gene identified by the Bacillus subtilis genome project (Mol. Microbiol. 10, 371-384 1993; Nature 390, 249-256 1997). The ipa-43d protein overexpressed in E. coli was purified to homogeneity and its properties were analyzed biochemically. The ipa-43d protein was found to be tightly associated with FMN and to be capable of reducing both nitrofurazone and FMN effectively...

BACKGROUND Asthma is a serious public health challenge because of the increasing number of people with a new diagnosis and consequently the increasing costs of medical treatment (direct and indirect). The aim of this study is to analyze available epidemiological data with respect to their spatial and temporal variability in the Silesian voivodeship. In addition, the costs incurred by the Nation...

BACKGROUND Catheter-associated urinary tract infection (CAUTI) is a major preventable cause of harm for patients in hospital. We aimed to establish whether short-term routine use of antimicrobial catheters reduced risk of CAUTI compared with standard polytetrafluoroethylene (PTFE) catheterisation. METHODS In our parallel, three group, multicentre, randomised controlled superiority trial, we e...

The enzymes responsible for the degradation of nitrofuran derivatives in rat small intestinal mucosa were examined in vitro.As a result,it was suggested that the initial reactions in the degradation of 2-(2-furyl)-3-(5-nitro-2-furyl)acrylamide(AF-2) and 5-nitro-2-furfural semicarbazone(nitrofurazone)are mainly catalyzed by xanthine oxidase , while that of 2-amino-5-[2-(5-nitro-2-fury1)-1-(2-fur...

The alcoholic extract of Guazuma ulmifolia was evaluated for their wound healing activity in Albino Wistar rats using chemically induced wound model. The experimental animals were chemically burned by conc HCL (80%), and then divided into four groups, control, standard (Nitrofurazone 0.2% w/w), low dose (125 mg/kg) and high dose (250mg/kg). The reepithelialization was evaluated by the reducing ...