Patients with chronic kidney disease (CKD) have high cardiovascular mortality and morbidity and a high risk for developing malignancy. Excessive oxidative stress is thought to play a major role in elevating these risks by increasing oxidative nucleic acid damage. Oxidative stress results from an imbalance between reactive oxygen/nitrogen species (RONS) production and antioxidant defense mechani...

This research was carried out to study the effect of ageing on antioxidant and biochemical changes of wheat (Triticum aestivum L.) seeds. The experiment laid out in completely randomized design (CRD) with four replications in Islamic Azad University, Boroujerd Branch, Boroujerd, Iran in 2015. The seeds of wheat (cv Sardari) were harvested at maturity and ageing treatments were done at 43° C wit...

Cigarette smoke (CS) is a rich source of radicals, predisposing the cell to oxidative stress resulting in inflammation. Chronic inflammation is a recognized risk factor for carcinogenesis. Cyclooxygenase-2 (COX-2) is a mediator of inflammatory pathway and may, therefore, contribute to carcinogenesis. There are several reports that suggest the association between CS and COX-2 associated risk to ...

Purslane(Portulaca oleracea L.) is a local plant in Iran that can easily breed. Chromium is a heavy metal that causes toxicity for the growth and development of plants. To study the effects of  potassium dichromate on growth, efficiency of photosystem II (Fv/Fm), cell membrane stability index (MSI), indexes of oxidative stress and antioxidant properties of purslane, an experiment was d...

BACKGROUND Natural honey (honey) is considered as a part of traditional medicine all over the world. It has both antimicrobial and antioxidant properties, useful in stimulation of wounds and burns healing and gastric ulcers treatment. The aim of this study, for the first time, was to investigate the antioxidant properties and protective role of honey against carcinogen chemical aflatoxin (AF) e...

BACKGROUND Islets from adult rat possess weak antioxidant defense leading to unbalance between superoxide dismutase (SOD) and hydrogen peroxide-inactivating enzymatic activities, catalase (CAT) and glutathione peroxidase (GPX) rending them susceptible to oxidative stress. We have shown that this vulnerability is influenced by maternal diet during gestation and lactation. METHODOLOGY/PRINCIPAL...

The purpose of this study was to investigate the possible antioxidant effect of metformin in high fructose fed diet-induced diabetic rats. The increased level of lipidperoxidation and altered levels of enzymatic and non enzymatic antioxidants were seen in high fructose fed consumed animals. The administration of metformin significantly normalized the altered levels of lipid peroxidation and ant...

Soil contamination by toxic trace metal elements, like barium (Ba), may stimulate various undesirable changes in the metabolic activity of plants. The plant responses are fast and with, direct or indirect, generation reactive oxygen species (ROS). To cope with stress imposed ROS production, plants developed a dual cellular system composed enzymatic non-enzymatic players that convert ROS, their ...