The main limitation of the study by Danesh-Meyer et al. was neither discussed nor mentioned. The time axis was not taken into account. The functional change after an acute event such as anterior ischemic optic neuropathy (AION) is immediate, but there is a delay before the anatomic changes take place. In this study, most of the patients with nonarteritic anterior ischemic optic neuropathy (NAIO...

The development of optical coherence tomography (OCT) has changed the clinical management of ophthalmic diseases by furthering the understanding of pathogenesis, as well as improving the monitoring of their progression and assisting in quantifying the response to treatment modalities in ophthalmic diseases. Initially, the two-dimensional configuration of the optic nerve head (ONH) and the thick...

A 51-year-old male was referred to the University Eye Clinic of Ioannina with nonarteritic anterior ischemic optic neuropathy (NAION) 12 hours after receiving sildenafil citrate (Viagra(®)). Examination for possible risk factors revealed mild hypercholesterolemia. Family history showed that his father had suffered from bilateral NAION. Although a cause-and-effect relationship is difficult to pr...

Dear Editor: We read with great interest, the case report on ischemic optic neuropathy (1). We would like to add a few points concerning the blood supply of the optic nerve and the correlation with the development of post-operative ischemic neuropathy. Actually, the perioperative or post-operative vision loss (postoperative ischemic neuropathy) is most likely due to ischemic optic neuropathy. I...

Seven patients, aged between 50 and 69 years, had typical features of nonarteritic anterior ischemic optic neuropathy (NAION) within 36 hours after ingestion of sildenafil citrate (Viagra) for erectile dysfunction. Six patients had vision loss within 24 hours after use of the agent. Final visual acuity in the affected eye ranged from 20/20 to light perception. Both eyes were affected in one ind...

Obesity hypoventilation syndrome (OHS) is defined as obesity (body mass index, >30 kg/m2) with daytime hypoventilation (PCO2, >45 mmHg) that is not secondary to cardiopulmonary or neurologic disease. Around 80–90% of the patients with OHS have obstructive sleep apnea and severe arterial oxygen desaturation. Obstructive sleep apnea has been found to be associated with a variety of eye diseases, ...

PURPOSE To determine the incidence of optic nerve damage due to nonarteritic anterior ischemic optic neuropathy (NAION) in the adult Chinese population. METHODS The Beijing Eye Study, a population-based, longitudinal study which included 4439 subjects (age 40+ years) in 2006, was repeated in 2006. In the follow-up examination, 3169 (71.4%) subjects participated. Optic disc photographs were as...

purpose: to compare ipsilateral and contralateral carotid wall thickness in patients with acute unilateral non-arteritic anterior ischemic optic neuropathy (naion). methods: this prospective case series included 17 (10 male and 7 female) patients with unilateral naion of less than 8 weeks' duration who underwent b-mode ultrasonography to measure intima-media thickness (imt) in the common c...