The presence of dark energy in the Universe challenges the Einstein’s theory 1 of gravity at cosmic scales. It motivates the inclusion of rotational degrees of freedom in 2 the Einstein-Cartan gravity, representing the minimal and the most natural extension of the 3 General Relativity. One can, consequently, expect the violation of the cosmic isotropy by 4 the rotating Universe. We study chiral...

In his De Poetics, Aristotle wrote that “the greatest thing by far is to be a master of metaphor. It is the one thing that cannot be learnt from others; it is also a sign of genius, since a good metaphor implies an intuitive perception of the similarity in dissirdars.” 1 By Aristotle’s standards, few of us would qualify as “a master of metaphor. ” In fact, merely distinguishing the term “metaph...

BACKGROUND Treatment of acute complete acromioclavicular (AC) dislocation is still controversial. Both non-surgical and surgical methods have been reported with similar results. In addition, once surgical treatment is chosen, a satisfactory surgical technique has not been developed yet. METHODS Sixty consecutive patients who sustained 60 acute complete AC dislocations were treated using corac...

INTRODUCTION. In Time-of-flight (TOF) angiography, fresh blood inflowing spins provide bright intravascular signal while static tissue signal suppression is obtained in the steady state with TR<<T1. At 1.5 and 3T, stronger background suppression is achieved with magnetization transfer (MT), and venous contribution is attenuated with saturation RF pulses. Ramp shaped RF pulses (TONE) can be used...

BACKGROUND A great amount of data has been accumulated on genetic variations in the human genome, but we still do not know much about how the genetic variations affect gene function. In particular, little is known about the distribution of nonsense polymorphisms in human genes despite their drastic effects on gene products. METHODOLOGY/PRINCIPAL FINDINGS To detect polymorphisms affecting gene...

Several lines of evidence indicate that the processes of mRNA turnover and translation are intimately linked and that understanding this relationship is critical to elucidating the mechanism of mRNA decay. One clear example of this relationship is the observation that nonsense mutations can accelerate the decay of mRNAs in a process that we term nonsense-mediated mRNA decay. The experiments des...

By adopting recent advances in music creation technologies, such as digital audio workstations and singing voice synthesizers, people can now create songs in their personal computers. Computers can also assist in creating lyrics or generating them automatically, although this aspect has been less thoroughly researched and is limited to rhyme and meter. This study focuses on the structural relat...