We report a case of extensive upper-lobe emphysema and lower-lobe pulmonary fibrosis consistent with combined pulmonary fibrosis and emphysema (CPFE) syndrome in a nonsmoker adult patient. Sequence analysis of surfactant protein C gene (SFTPC, MIM 178620) and ATP-binding cassette subfamily A member 3 gene (ABCA3, MIM 601615) identified no mutation in SFTPC gene but compound heterozygosity in AB...

A 20-year-old white female nonsmoker presented to the pulmonary function laboratory for a methacholine challenge test. The patient denied wheezing, dyspnea, cough, or chest tightness. In fact, she competes in collegiate basketball and softball without respiratory complaints. She stated that her primary care physician wanted to “screen her for asthma,” because her father is asthmatic. Her medica...

The masimum effort flow-volume (MFV) loops of 82 subject8 were analyzed dong with standard spirometric me&urementa Thirty-eight ;ere normal smokers and nonmoken. Ninetan had d c t i v e disease and 25 had o ~ c t i v e disease. The means of the maximum e x p b tog and inspiratory Bows at pePL, and at 75,50 and 25 percent VC with their ratios are determined for dl groupe. The location of PEF in ...

A 77-year-old black woman who was a lifelong nonsmoker presented to our office for evaluation of worsening dyspnea over the last year that had severely limited her activities of daily living. Her medical history included type 2 diabetes, hypertension, and pacemaker placement. She reported paroxysmal nocturnal dyspnea and dry cough. She denied fevers, chills, chest pain, hemoptysis, or weight lo...

This study examined the communication effects of smoking cessation by using message framing (positive messages/negative messages) and audience situation (smoker/nonsmoker and high/low self-efficacy). The study used 207 valid homogeneous subjects and a between-subject experiment method was employed for analyses. The results showed that the communication effects were influenced by the interactive...

Serial measurements of transfer factor of lung and its constituent components along with FVC and EFR25-75% were undertaken in 20 healthy nonsmoker adult males thrice on the same day. All the lung transfer components decreased as the day advanced, though reduction was statistically significant for Tlco and VA only. These changes were present in association with reduction in FVC and EFR25.75% ind...

DESCRIPTION A 16-year-old previously well female, nonsmoker, without significant medical history, received an injection of lidocaine with epinephrine from her dermatologist, delivered in his office, to the radial and ulnar aspects of the middle phalanx of her long finger before having a skin lesion (wart) removed. No tourniquet was used. Eight hours later, the patient presented to the emergency...