Background: The Pelger-Huet anomaly dominantly is a rare and benign inherited defect of terminal neutrophil differentiation. Although neutrophil migration may be minimally impaired, granulocytes function is otherwise normal association abnormalities such as ocular, musculoskeletal are reported very rare. Case: An eight year-old boy with good consciousness but severe muscular atrophia and diffic...

The author provides a preliminary framework for a systematic and dynamic understanding of dissociation through a consideration of the theories of Hughlings Jackson. Jackson's ideas are briefly reviewed. He saw the proper scientific investigation of mental illness as an experimental investigation of mind. Accordingly, his argument begins with this fundamental concept. His views of the brain-mind...

Current research on artificial consciousness is focused on phenomenal consciousness and on functional consciousness. We propose to shift the focus to self-consciousness in order to open new areas of investigation. We use an existing scenario where self-consciousness is considered as the result of an evolution of representations. Application of the scenario to the possible build up of a consciou...

In recent years, there has been much focus on the apparent heterogeneity of schizophrenic symptoms. By contrast, this article proposes a unifying account emphasizing basic abnormalities of consciousness that underlie and also antecede a disparate assortment of signs and symptoms. Schizophrenia, we argue, is fundamentally a self-disorder or ipseity disturbance (ipse is Latin for "self" or "itsel...

What is the level of consciousness of the psychedelic state? Empirically, measures of neural signal diversity such as entropy and Lempel-Ziv (LZ) complexity score higher for wakeful rest than for states with lower conscious level like propofol-induced anesthesia. Here we compute these measures for spontaneous magnetoencephalographic (MEG) signals from humans during altered states of consciousne...

case: a 26-year-old man referred to emergency service with coma, bradypnea (respiratory rate = 4 breaths per minute) and pinpoint pupil. on chest auscultation, diffuse coarse crackle and on abdominal auscultation, decrease of abdominal sounds were found. at first evaluation, pulse oximetry showed 19% saturation of oxygen. after oxygen therapy with facial mask and infusion of 8.4 mg naloxone in ...