The amino-terminal domain of Nic96p physically interacts with the Nsp1p complex which is involved in nucleocytoplasmic transport. Here we show that thermosensitive mutations mapping in the central domain of Nic96p inhibit nuclear pore formation at the nonpermissive temperature. Furthermore, the carboxyterminal domain of Nic96p functionally interacts with a novel nucleoporin Nup188p in an allele...

background: the goal of the present study was to report the results of two parallel works in which the incidence of fetal deaths and also congenital malformations among the progenies of the iranian chemical victims were studied. methods: the subjects were progenies of a randomly selected population from survivors of chemical attacks during iran-iraq conflict. totally 807 male cases ranged 18-85...

reproductive abnormalities cause major losses of sheep production. abattoir materials were used todetermine the extent of reproductive wastage. reproductive tracts were collected from 524 ewes slaughtered at urmia slaughter-house in urmia, northwest of iran, during a period of 12 months. overall, 30.10% of the ewes examined were pregnant. a total of 149 (28.44%) tracts developed acquired reprod...

introduction pelvic pain results from many causes such as primary dysmenorrhea, uterine anomalies, menstrual outflow obstruction, endometriosis, myoma and adenomyosis. this study reports on a rare case of non-communicating functional rudimentary horn. case presentations a 15-year-old nulligravida young woman with a history of severe intermittent pelvic pain presented a 4-5 centimeter mass. a su...

BACKGROUND White matter (WM) abnormalities are common in cirrhotic patients and possibly contribute to hepatic encephalopathy (HE), a frequent neuropsychiatric complication of cirrhosis. However, little is known about these WM abnormalities and their relationship to neurocognitive deficits in patients with HBV-related cirrhosis. METHODS Three-dimensional T1-weighted magnetic resonance imaging...

background: cardiac manifestations that occur in a majority of patients with organophosphate (op) poisoning may range from innocuous electrocardiographic manifestations, such as sinus tachycardia, to life-threatening complications, including cardiogenic pulmonary edema and myocardial necrosis. in this study, we evaluated the various electrocardiographic manifestations in patients with op poison...

background: hematological abnormalities are a common complication of hiv infection and occur in all stages of the infection. these abnormalities increase as the disease advances. we aimed to evaluate the diagnostic utility of bone marrow sampling in hiv-positive patients. methods: 40 hiv-infected individuals were screened for hematological abnormalities. investigations such as iron studies, hem...