We review Quasielastic (QE) inclusive and semi–inclusive neutrino/antineutrino Charged Current (CC) and Neutral Current (NC) induced nuclear reactions at intermediate energies. We pay special attention to nuclear corrections besides Pauli blocking: Long and Short range nuclear correlations (RPA and SRC) and particle and hole Spectral Functions (SF). We also critically review the use of the Plan...

A new Geant4 physics list is prepared for nuclear physics applications in the domain dominated by spallation. The C++ translation of original Fortran INCL intra-nuclear cascade and ABLA fission/de-excitation codes are used in the physics list. The INCL model prepared is well established for targets heavier than Aluminium and projectile energies from ∼ 150 MeV up to 2.5 GeV ∼ 3 GeV. Validity of ...

A new method for simulation of nuclear γ cascades by the Monte Carlo technique is described. It makes it possible to generate artificially individual events of the γ-cascade decay of neutron capturing states in heavy nuclei. For the purpose of determination of lifetimes of nuclear levels by the GRID method the previously developed Mean Free Path Approach for modelling atomic collisions and thei...

We review Quasielastic (QE) inclusive and semi–inclusive neutrino/antineutrino Charged Current (CC) and Neutral Current (NC) induced nuclear reactions at intermediate energies. We pay special attention to nuclear corrections besides Pauli blocking: Long and Short range nuclear correlations (RPA and SRC) and particle and hole Spectral Functions (SF). We also critically review the use of the Plan...

The endoplasmic reticulum (ER) is the major Ca(2+) store inside the cell. Its organisation in specialised subdomains allows the local delivery of Ca(2+) to specific cell areas on stimulation. The nuclear envelope (NE), which is continuous with the ER, has a double role: it insulates the nucleoplasm from the cytoplasm and it stores Ca(2+) around the nucleus. Furthermore, all the constituents ...

The original Lindhard-Scharff-Schiøtt (LSS) theory and the more recent Tilinin theory for calculating the nuclear and electronic stopping powers of slow heavy ions are compared with predictions from the SRIM code by Ziegler. While little discrepancies are present for the nuclear contribution to the energy loss, large differences are found in the electronic one. When full ion recoil cascade simu...

A formation zone intranuclear cascade model is applied to peripheral nucleus-nucleus collisions. We calculate the excitation energies of prefragments, treat their further nuclear disintegration and introduce a model for nuclear deexcitation by photon emission. Results are compared to data on target associated particle production in nucleus-nucleus collisions. We discuss implications of these mo...

Differential subcellular localization of EBP50 leads to its controversial role in cancer biology either as a tumor suppressor when it resides at the membrane periphery, or a tumor facilitator at the nucleus. However, the mechanism behind nuclear localization of EBP50 remains unclear. A RNA interference screening identified the downstream effector of the Ras-ERK cascade, RSK1, as the molecule un...

Nuclear protein peptidyl-prolyl isomerase Pin1-mediated prolyl isomerization is an essential and novel regulatory mechanism for protein phosphorylation. Therefore, tight regulation of Pin1 localization and catalytic activity is crucial for its normal nuclear functions. Pin1 is commonly dysregulated during oncogenesis and likely contributes to these pathologies; however, the mechanism(s) by whic...