This paper focuses on segmenting dynamic magnetic resonance (MR) images of the human heart stored in a database. Heart MR images are dynamic, as the size and shape of a person’s heart vary in time. Active Shape Model segmentation was used to segment dynamic images of the heart. The input data is a points file of a set of random points. This method is economical since points of all the frames ne...

How will the Treaty on Prohibition of Nuclear Weapons (TPNW) shape broader pursuit nuclear abolition? TPNW critics have argued that new agreement is likely to fuel divisions between and non-nuclear-weapon sates, undermining consensus hampering existing efforts at reducing eliminating arms. In this commentary, I argue one TPNW’s key strengths contributions precisely it pierces feigned abolitioni...

introduction: morphology and ultra-structure of myoid and sertoli cells were studied in patients with non-obstructive azoospermia who were admitted to testicular sperm extraction (tese) and intracytoplasmic sperm injection (icsi), by transmission electron microscopy (tem). materials and methods: 12 biopsies of testicular tissues from patients with non-obstructive azoospermia referred to royan i...

Although a great deal is known about the signaling events that promote nuclear translocation of NF-κB, how cellular biophysics and the microenvironment might regulate the dynamics of this pathway is poorly understood. In this study, we used high-content image analysis and Bayesian network modeling to ask whether cell shape and context features influence NF-κB activation using the inherent varia...

How cells maintain nuclear shape and position against various intracellular and extracellular forces is not well understood, although defects in nuclear mechanical homeostasis are associated with a variety of human diseases. We estimated the force required to displace and deform the nucleus in adherent living cells with a technique to locally pull the nuclear surface. A minimum pulling force of...

Results of observations of low energy nuclear and electron recoil events in liquid xenon scintillator detectors are given. The relative scintillation efficiency for nuclear recoils is 0.22 ± 0.01 in the recoil energy range 40 keV 70 keV. Under the assumption of a single dominant decay component to the scintillation pulse-shape the log-normal mean parameter T0 of the maximum likelihood estimator...

Alterations in nuclear morphology are closely associated with essential cell functions, such as cell motility and polarization, and correlate with a wide range of human diseases, including cancer, muscular dystrophy, dilated cardiomyopathy and progeria. However, the mechanics and forces that shape the nucleus are not well understood. Here, we demonstrate that when an adherent cell is detached f...