The nuclear envelope (NE) of eukaryotic cells provides a physical barrier for messenger RNA (mRNA) and the associated proteins (mRNPs) traveling from sites of transcription in the nucleus to locations of translation processing in the cytoplasm. Nuclear pore complexes (NPCs) embedded in the NE serve as a dominant gateway for nuclear export of mRNA. However, the fundamental characterization of ex...

Background: Varicocele has been repeatedly implicated as a cause of infertility in selected men. Previous studies have showed high levels of seminal oxidative stress, as evidenced by increased levels of ROS and reduced total antioxidant capacity in varicocele men, suggesting that sperm dysfunction in varicocele patients may be partly related to oxidative stress. Thus current study was designed ...

Medicine is now undertaking a paramount revolution that will alter the nature of healthcare from reactive to proactive. It is imperative to integrate experimental and computational investigation in order to appreciate complex biological systems in the era of precision medicine. In light of this revolution, we necessitate to precision medicine means such as systems approaches (genomics, radiogen...

Myocardial perfusion SPECT is one of the most common imaging techniques performed in nuclear medicine departments. To avoid misleading interpretation, it is necessary to address the quality control and technical problems. The truncation artifact occurs when the patient size is large relative to the field of view of the camera, causing false perfusion defects in the LV myocardium, misinterpreted...

Abstract Particle identification techniques are fundamental tools in nuclear physics experiments. Discriminating particles or nuclei produced interactions allows to better understand the underlying mechanisms. The energy interval of these reactions is very broad, from sub-eV up TeV. For this reason, many different approaches have been developed, often combining two more observables. This paper ...