BACKGROUND AND OBJECTIVES Secondary hyperparathyroidism is common among patients with ESRD. Although medical therapy for secondary hyperparathyroidism has changed dramatically over the last decade, rates of parathyroidectomy for secondary hyperparathyroidism across the United States population are unknown. We examined temporal trends in rates of parathyroidectomy, in-hospital mortality, length ...

BACKGROUND/AIMS One of the causes of uncontrolled secondary hyperparathyroidism (sHPT) is patient's poor drug adherence. We evaluated the clinical benefits of an integrated care approach on the control of sHPT by cinacalcet. METHODS Prospective, randomized, controlled, multicenter, open-label study. Fifty hemodialysis patients on a stable dose of cinacalcet were randomized to an integrated ca...

Oral manifestations of severe secondary hyperparathyroidism include maxillary and mandibular deformities, brown tumors, dental abnormalities, and metastatic calcification of soft tissues. We report on a chronic hemodialysis (HD) woman with severe, uncontrolled secondary hyperparathyroidism and a painful, nontender mass in the floor of her mouth. The most likely clinical diagnosis was a bone tum...

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BACKGROUND Secondary hyperparathyroidism (SHPT) is associated with adverse outcomes in patients receiving maintenance dialysis. Parathyroidectomy is a treatment for SHPT; whether parathyroidectomy utilization varies geographically in the US is unknown. METHODS A retrospective cohort analysis was undertaken to identify all patients aged 18 years or older who were receiving in-center hemodialys...

There are many unanswered questions about how to manage secondary hyperparathyroidism and associated alterations in mineral metabolism in patients with end-stage renal disease. We provide commentary on an observational study by Komaba et al. that presents interesting new insights into the long-standing controversy related to the impact of parathyroidectomy on survival of hemodialysis patients.

Mnemonics are learning techniques that make for greater memorability and help improve long term memory. Commonly encountered mnemonics are usually verbal, such as an acronym, a short poem or mathematical relations for numerical data. Mnemonics may also be visual, kinesthetic or auditory. Mnemonics are based on the observation that the human mind much more easily remembers and retrieves surprisi...

2.1 Nos pacientes com DRC estágios III a V, os níveis ideais de PTH não são conhecidos. No entanto, sugerimos que os pacientes com níveis de PTH acima do limite superior de referência para o método sejam avaliados quanto à presença de hipocalcemia, hiperfosfatemia ou fração de excreção de P elevada, e deficiência de 25-hidroxivitamina D (25-vit D). Se forem detectadas alterações nesses parâmetr...

ATTENTION has been drawn to the possible adverse effects of anticonvulsant drugs on bone metabolism by a number of reports in recent years (Dent et al, 1970; Richens and Rowe, 1970; Hunter et al, 1971; Lifshitz and Maclaren, 1973; Stamp, 1974; British Medical Journal, 1976). The aim of the present study was to investigate this potentially serious side-effect of anticonvulsant therapy in the set...

Objectives: To explore the diagnostic value of 99mTc-Sestamibi multiple-phase static planar imaging and SPECT/CT in secondary hyperparathyroidism. Methods: This was a retrospective analysis of 40 cases of clinically diagnosed secondary hyperparathyroidism with multiple-phase static planar imaging, 15 min SPECT/CT fusion imaging, and ultrasonography. All cases were confirmed by pathological exam...