نتایج جستجو برای: oc symptoms

تعداد نتایج: 291296  

Journal: :Neuropsychologia 2009
Theo O J Gründler James F Cavanagh Christina M Figueroa Michael J Frank John J B Allen

Hyperactive cortico-striatal circuits including the anterior cingulate cortex (ACC) have been implicated to underlie obtrusive thoughts and repetitive behaviors in obsessive-compulsive disorder (OCD). Larger error-related negativities (ERNs) in OCD patients during simple flanker tasks have been proposed to reflect an amplified error signal in these hyperactive circuits. Such amplified error sig...

Journal: :The Journal of clinical investigation 2015
Adel Ersek Ke Xu Aristotelis Antonopoulos Terry D Butters Ana Espirito Santo Youridies Vattakuzhi Lynn M Williams Katerina Goudevenou Lynett Danks Andrew Freidin Emmanouil Spanoudakis Simon Parry Maria Papaioannou Evdoxia Hatjiharissi Aristeidis Chaidos Dominic S Alonzi Gabriele Twigg Ming Hu Raymond A Dwek Stuart M Haslam Irene Roberts Anne Dell Amin Rahemtulla Nicole J Horwood Anastasios Karadimitris

Glycosphingolipids (GSLs) are essential constituents of cell membranes and lipid rafts and can modulate signal transduction events. The contribution of GSLs in osteoclast (OC) activation and osteolytic bone diseases in malignancies such as the plasma cell dyscrasia multiple myeloma (MM) is not known. Here, we tested the hypothesis that pathological activation of OCs in MM requires de novo GSL s...

Journal: :Psychiatry research 2009
Vasileios Boulougouris Samuel R Chamberlain Trevor W Robbins

Several axis-I neuropsychiatric disorders are characterised by repetitive motor habits suggestive of underlying inhibitory dyscontrol, and may constitute members of a putative obsessive-compulsive (OC) spectrum. Notable examples include obsessive-compulsive disorder (OCD) and trichotillomania (repetitive hair-pulling). Multiple tiers of evidence link these conditions with underlying dysregulati...

2017
Maria Koutsaki Massimo Libra Demetrios A. Spandidos Apostolos Zaravinos

Ovarian cancer (OC) is the most lethal gynecological malignancy. Its insidious nature, manifesting with little to no symptoms until the disease progresses to metastasis, along with a wide diversity of histological subtypes and corresponding clinical behavior, poses significant therapeutic challenges. The genetic profiling of this aggressive tumor and its subtypes has led to the identification o...

Journal: :Hormones 2015
Panagiota Pervanidou Despoina Bastaki Giorgos Chouliaras Katerina Papanikolaou Christina Kanaka-Gantenbein George Chrousos

OBJECTIVE Pediatric obesity commonly co-exists with emotional and behavioral disorders, while disturbed cortisol concentrations have been reported in both obese and chronically stressed individuals with anxiety and/or depression. We investigated the prevalence of internalizing and externalizing problems, reported by both parents and children, in a clinical population of obese children (OC) comp...

Journal: :Fertility and sterility 2006
Lourdes Ibáñez Francis de Zegher

Polycystic ovary syndrome (PCOS) is a variable disorder that is characterized in adolescents and young women by a broad spectrum of anomalies, including hyperandrogenemia, insulin resistance, dyslipidemia, body adiposity and low-grade inflammation. At present, there is no approved therapy for PCOS. Recent studies indicate that a low-dose combination of flutamide (Flu; a generic androgen-recepto...

Journal: :Neuropsychiatric Disease and Treatment 2005
Bruno Aouizerate Dominique Guehl Emmanuel Cuny Alain Rougier Pierre Burbaud Jean Tignol Bernard Bioulac

The pathophysiology of obsessive-compulsive disorder (OCD) remains unknown. However, increasing attention has been paid to the putative role of the serotoninergic system, the strongest evidence being based on the widely demonstrated efficacy of serotonin (5HT) reuptake inhibitor antidepressants in the treatment of OCD. The therapeutic effects are correlated with changes in peripheral parameters...

Journal: :International Journal of Mental Health and Addiction 2022

Abstract The present study investigated the patterns of mutual associations between maladaptive daydreaming-related variables (MD, i.e., interference with life and somatosensory retreat), psychopathological symptoms (i.e., depression, anxiety, somatization, obsessive–compulsive, interpersonal sensitivity, psychoticism), emotion regulation strategies cognitive reappraisal expressive suppression)...

Journal: :European Journal of Mental Health 2022

Introduction: An increase in obsessive-compulsive disorder (OCD) was predicted as a consequence of the COVID-19 pandemic and measures established for controlling it. Aims: This review seeks to analyze relationship between (OCD), particular pandemic’s effect on prevalence (OC) symptoms, predisposing factors, interventions carried out, their effectiveness proposal future situations similar one st...

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