The incidence of syphilis in the United States has increased markedly over the last decade, particularly among men who have sex with men (MSM). Although uncommon, ocular involvement is a potentially devastating clinical manifestation of syphilis. Human immunodeficiency virus (HIV) infection appears to increase the risk of ocular syphilis. Because of the lack of pathognomonic features for ocular...

Ocular complications are common in acquired immunodefi ciency syndrome (AIDS) and occur in 50-75% of patients throughout the course of their illness. Syphilis is the most common bacterial eye infection in these patients and most often presents as uveitis or an optic nerve disease. This condition can manifest as episcleritis, scleritis, dacryoadenitis, anterior uveitis, intermediate uveitis, pap...

The recently modified fluorescence inhibition test for antibodies to toxoplasmosis is safe and relatively simple to perform. It appears to detect antibodies early in the course of acute systemic infection but is less sensitive than either the dye test or hemagglutination test in detecting chronic infection. Although hemagglutinating antibodies develop later than dye test antibodies in the cours...

The atypical, or nontuberculous, mycobacteria are opportunistic pathogens that usually cause infection following accidental trauma or surgery. These organisms are ubiquitous in nature but have been found with increasing frequency in other environments that include medical offices and surgical suites. Management of atypical mycobacterial ocular infections can be difficult because in vitro antibi...

Endogenous endophthalmitis is an intraocular infection that results from hematogenous spread of organisms from a distant source of infection. Facial cellulitis is rarely reported as a focus of infection. We report a case of 51-year-old unconscious woman presenting with fever, facial swelling, and decreased visual acuity secondary to facial cellulitis, endogenous endophthalmitis and end-stage re...

Adenoviruses are a common cause of viral eye disease in humans. Recently, new antiviral drugs have been developed, which possess promising anti-adenovirus activity. In order to test these drugs, an ocular model of adenovirus infection was developed in 10 Hollander rabbits following topical, intrastromal and subconjunctival inoculation with a standard laboratory serotype (Adenovirus type 5 from ...

BACKGROUND The purpose of this case report is to describe clinical and angiographic findings of retinal vasculitis in acute Toxocara canis neuroretinitis associated with systemic infection. FINDINGS A 16-year-old male presented with a 1 week history of left eye pain, floaters, and decreased visual acuity. Ocular examination was consistent with neuroretinitis and retinal vasculitis. Fluorescei...

BACKGROUND Dengue virus infection is on the rise and there is increasing number of ocular complications that are being reported. Most common ocular complications are macular edema, macular hemorrhages, and foveolitis. There are case reports on branch retinal vessel occlusions. Most of the ocular complications are attributed to the bleeding tendency and transudative process in dengue viral infec...

H.erpesvirus hominis is a highly successful parasite, having developed a relationship to the host which assures its perpetuation without seriously disturbing the host population. From 50 to 90 per cent of the adult population has neutralizing antibodies to herpes simplex, indicating previous infection, but most of these affected individuals show no clinical manifestation of disease. Ocular herp...

PURPOSE To compare the efficacy and safety of 0.1% dexamethasone/0.3% netilmicin (Netildex), with that of 0.1% dexamethasone/0.3% tobramycin (Tobradex) in the treatment of external ocular inflammation requiring antibiotic therapy. METHODS In this randomized, double-blind study, 139 subjects with conjunctival inflammation associated with signs of ocular infection were treated with Netildex (n ...