AIM Presenting a rare complication of an odontogenic infection extending to the orbit. BACKGROUND A 45-year-old male patient reported with periorbital swelling of eyelids, of the left eye, foul smelling nasal discharge and a pus draining sinus on the left lower eyelid area. CASE DESCRIPTION The patient gave history of pain in the left upper first molar tooth 1 week back. His intraoral exami...

In this report, we describe a case of brain abscess due to odontogenic infection. A 53-year-old female who had been suffering from headache and trismus for two weeks visited the Department of Oral and Maxillofacial Surgery at the Sun Dental Hospital (Daejeon, Korea). Even after several routine tests, we still could not make a diagnosis. However, after the combined multidisciplinary efforts of o...

Background. The aim of this study was to investigate myofibroblast (MF) density in a broad spectrum of odontogenic cysts and tumors and the relation between the density of MFs and the clinical behavior of these lesions. Methods. A total of 105 cases of odontogenic lesions, including unicystic ameloblastoma (UAM), solid ameloblastoma (SA), odontogenic keratocyst (OKC), dentigerous cyst (DC), rad...

Odontogenic infections resulting in osteomyelitis of the mandible are common. However, osteomyelitis of the coronoid process as a direct consequence of third molar infection is rare. The following report describes such a case in an 18-year-old female as a severe complication following third molar removal. Despite aggressive antimicrobial therapy and indicated treatment approach following microb...

The overuse of antibiotics and the emergence of antibiotic-resistant bacterial strains is a global concern. This concern is also of importance in terms of the oral microbiota and the use of antibiotics to deal with oral and dental infections. The aim of this paper was to review the current literature on the indications and use of antibiotics and to make recommendations for their prescription in...

In the last few years, role of oral microbiota in setting diseases such as caries, periodontal disease, cancer and systemic infections, including rheumatoid arthritis, cardiovascular disease brain abscess (BA), has attracted attention physicians researchers. Approximately 5–7% all BAs have an odontogenic origin, representing important pathological condition with a high morbidity mortality. A sy...

Midkine (MK; a low molecular weight heparin-binding growth factor) is a multifunctional cytokine. MK plays a role in morphogenesis of many organs including teeth through epithelial-mesenchymal interactions. We immunohistochemically examined MK expression in various human odontogenic tumors. There was no difference in positive rate and intensity of MK between benign odontogenic tumors and their ...

The oral cavity may represent a reservoir of Pseudomonas aeruginosa, especially in patients with periodontitis; this makes treatment more difficult and, in the case of opportunistic infections, may worsen the conditions of debilitated patients, such as the elderly and immunossupressed. The present investigation aims at using a clinical case to discuss the possibility of a secondary infection of...

BACKGROUND The aims of this study were to investigate the immunolocalization of ezrin and its relationship with the podoplanin expression in keratocystic odontogenic tumors. MATERIAL AND METHODS The immunohistochemical expressions of ezrin and podoplanin by odontogenic epithelium were evaluated in keratocystic odontogenic tumors using monoclonal antibodies. RESULTS Our results showed strong...

The Odontogenic Keratocyst (OKC), first described by Phillipsen in 1956, has been reclassified as odontogenic neoplasm and has been renamed as Keratocystic Odontogenic Tumor (KCOT) as reported in WHO classification of head and neck tumors in 2005. Odontogenic keratocysts are benign intraosseous tumors of odontogenic origin that occur most commonly in the jaw. In particular, they have a predilec...