In the past the benign cementoblastoma was recognized in the World Health Organization’s classification of odontogenic tumors as one of the cementoma neoplasias. Recently the benign cementoblastoma is included into ‘Mesenchyme and/or odontogenic ectomesenchyme, with or without odontogenic epithelium’ odontogenic tumors. Benign cementoblastoma has characteristic radiologic and microscopic featur...

Odontogenic neoplasms encompass a group of lesions with a varied clinical picture and biological behavior ranging from indolent hamartomatous proliferation to locally aggressive benign tumors and their very aggressive malignant counterparts. The benign neoplasms are normally slow growing, indolent with no invasive potential. However, there exists a few locally aggressive benign odontogenic tumo...

The calcifying epithelial odontogenic tumor (CEOT) is a rare benign odontogenic neoplasm that accounts for approximately 1% of all odontogenic tumors. Its origin is controversial as well as its true malignant potential. A case of an advanced CEOT associated with an impacted right second molar in the mandible of a young black female patient is presented. Computed tomography imaging, radiographic...

Adenomatoid odontogenic tumor (AOT) is an uncommon tumor of odontogenic origin, constituting only 3% of all odontogenic tumors. AOT is characterized histologically by the formation of duct-like structures with amyloid-like deposits. An 18-year-old male presented with right chek swelling. CT scan revealed well-defined expansile heterogeneous mass with central hypodensity. Patient underwent excis...

Dysregulation of TGF,62, a modulator of cell growth and differentiation, can result in uncontrolled growth and tumor formation. Our comparative studies on the expression of TGF (2 mRNA and protein indicate that TGF (2 may primarily be a regulator of epithelial differentiation during tooth development (between 13 and 20 gestational wk) and tumorigenesis of odontogenic neoplasms. A paracrine mode...

Dysregulation of TGF beta 2, a modulator of cell growth and differentiation, can result in uncontrolled growth and tumor formation. Our comparative studies on the expression of TGF beta 2 mRNA and protein indicate that TGF beta 2 may primarily be a regulator of epithelial differentiation during tooth development (between 13 and 20 gestational wk) and tumorigenesis of odontogenic neoplasms. A pa...