BACKGROUND Olfactory disorders are common complaints in ENT clinics. We investigated causes and relevant features of olfactory disorders and the need for gustatory testing in patients with olfactory dysfunction. MATERIAL/METHODS A total of 140 patients seeking medical consultations were enrolled. All patients were asked about their olfactory disorders in a structured interview of medical hist...

The goal of this study was to investigate the spatial organization of olfactory glomeruli and of substances relevant to olfactory sensory neuron activity in the developing agnathan, the sea lamprey Petromyzon marinus. A 45-kD protein immunoreactive to G(olf), a cAMP-dependent olfactory G protein, was present in the ciliary fraction of sea lamprey olfactory epithelium and in olfactory sensory ne...

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Within the central nervous system, the olfactory system fascinates by its developmental and physiological particularities, and is one of the most studied models to understand the mechanisms underlying the guidance of growing axons to their appropriate targets. A constellation of contact-mediated (laminins, CAMs, ephrins, etc.) and secreted mechanisms (semaphorins, slits, growth factors, etc.) a...

the present study is related to the histochemical investigations on the changes in the intensity of reactions of axons, acid and neutral mucopolysaccharides, biologically active macromolecules, particularly glycogen and protein component as well as alkaline phosphatase (alpase) and adenosine triphosphatase (atpase) in the cells lining the olfactory epithelium of catla catla . the intense reacti...

When the results of the standard olfactory acuity test assigned to about 8,000 patients with dysosmia, who visited our olfactory outpatient clinic of the Department of Otorhinolaryngology of Showa University Hospital, were analyzed, it was found that a difference in olfactory acuity loss between recognition threshold and detection threshold was over 1.0 in many of them. Since normal Subjects sh...

Elasmobranch fishes are thought to possess greater olfactory sensitivities than teleost fishes due in part to the large amount of epithelial surface area that comprises their olfactory organs; however, direct evidence correlating the size of the olfactory organ to olfactory sensitivity is lacking. This study examined the olfactory morphology and physiology of five distantly related elasmobranch...

PURPOSE The aim of this study was to assess whether migration of thallium-201 ((201)Tl) to the olfactory bulb were reduced in patients with olfactory impairments in comparison to healthy volunteers after nasal administration of (201)Tl. PROCEDURES 10 healthy volunteers and 21 patients enrolled in the study (19 males and 12 females; 26-71 years old). The causes of olfactory dysfunction in the ...

The olfactory system provides an excellent model in which to study cell proliferation, migration, differentiation, axon guidance, dendritic morphogenesis, and synapse formation. We report here crucial roles of the Arx homeobox gene in the developing olfactory system by analyzing its mutant phenotypes. Arx protein was expressed strongly in the interneurons and weakly in the radial glia of the ol...

* Present address: Biological Research Lab., Tanabe Seiyaku Co ., Ltd., Osaka, Japan. Abstract-In order to clarify the neural mechanisms underlying the hyperemotion ality induced by bilateral olfactory bulb ablations in rats, changes in emotional be havior were measured after various parts of the secondary olfactory structures had been lesioned and olfactory bulb ablations had been carried out....