The aims of this study were to assess the presence and the frequency of isthmuses in the mesial roots of the maxillary and mandibular first molars (at two resection levels from the apex), and to compare the findings obtained by macroscopic observation (MO) and operating microscope (OM). Forty maxillary and 40 mandibular mesial roots were observed at 3 and 5 mm from the apex initially macroscopi...

We analyzed the outer membrane (OM) ultrastructure of four pathogenic members of the family Spirochaetaceae by freeze fracture. The OM of Treponema pallidum subsp. pertenue contained a low intramembranous particle concentration, indicating that it contains few OM transmembrane proteins. The concave OM fracture faces of Treponema hyodysenteriae and Borrelia burgdorferi contained dense population...

OBJECTIVES In recent years welfare in Denmark has increased which might be expected to reduce otitis media (OM) incidence. We examined the age-specific incidence of OM in a nation-wide cohort of children aged 0-7 years born in 1996-2003 (Danish National Birth Cohort, DNBC). Only selection was ability to understand and speak Danish. METHODS Information of OM and ventilation tubes (VT) was coll...

Otitis media (OM) has numerous presentations in children. Together with conventional medical therapies aimed to prevent and/or treat OM, a rising number of complementary and alternative medicine (CAM) treatment options can be offered. Since OM is common in children, parents may ask healthcare professionals about possible CAM therapies. Many physicians feel that their knowledge is limited regard...

BACKGROUND Nutrients related to serum vitamin D level were previously shown to be significantly associated with the risk of many chronic diseases. This study aimed to assess potential relationships between serum vitamin D level and otitis media (OM) risk. METHODS PubMed, EMBASE, and Cochrane Library databases were searched till Aug 18, 2015 for studies of quantitative OM risk estimates in rel...

The objectives of the study were to (i) investigate whether short term mineralization varies to a greater extent by charring organic matter (OM) or by exposure to different mineral surfaces, (ii) examine the effect of clay mineralogy on mineralization of either charred or uncharred OM and (iii) quantify these differences in mineralization in the context of C evolution during charring. Mineraliz...

From the ca;px stock, which is the progenitor of Om mutants caused by insertions of the tom retrotransposon, 50 kb of genomic DNA including the Om(1D) locus was cloned by tom tagging and chromosome walking. Southern blot analyses of six Om(1D) mutants exposed one or two tom elements inserted at five nonrandom sites within an 18-kb distal segment of the restriction map; the phenotypic uniformity...

OM occurs in 85% of patients receiving head/neck irradiation alone and in 95% of head and neck cancer patients treated with chemoradiation. The incidence and severity of OM vary with different treatment regimens, but all patients with OM share the same pathogenesis: an interference with normal epithelial cell turnover, leading to direct and indirect destruction of the mucosal lining.[1–4] Subse...

Two studies (ROADMAP and ORIENT) evaluating the renoprotective effects of olmesartan medoxomil (OM) in patients with type 2 diabetes suggested OM is associated with increased cardiovascular mortality. We conducted a thorough QTc study to evaluate the effects of OM on cardiac repolarization. A randomized, double-blind, phase 1 study was conducted per E14 Guidance to assess the effects of single ...