BACKGROUND We recently reported that treatment with intrauterine insemination and controlled ovarian stimulation (IUI-COS) did not increase ongoing pregnancy rates compared with expectant management (EM) in couples with unexplained subfertility and intermediate prognosis of natural conception. Long-term cost-effectiveness of a policy of initial EM is unknown. We investigated whether the recomme...

• Work supported in part by the U.S. Office of Naval Research, under Contract No.NONR-1224(59). 1 G. Veneziano, Nuovo Cimento 57A,190 (1968). 2 K. Bardakci and H. Ruegg, Phys. Letters 28B, 242 (1968). 3 M.A. Virasoro, Phys. Letters 22,37 (1969). 4 H.-M.Chan,Phys.Letters 28B,425 (1969). 5 H.-M.Chan and S. T. Tsou, CERN Preprint TH 969,1968 (unpublished) . 6 H.-M.Chan and S.T. Tsou, Phys.Letters ...

In this retrospective study, the utility of preimplantation genetic screening (PGS) in patients with advanced maternal age is evaluated. The patient population consisted of women aged 38-44years and included in a regular IVF programme with or without PGS analysis. Transfer rate, ongoing implantation rate and ongoing pregnancy rate were the main outcome parameters measured. A trend of better ong...

OBJECTIVE To compare the effectiveness of an electrocautery strategy with ovulation induction using recombinant follicle stimulating hormone in patients with polycystic ovary syndrome. DESIGN Randomised controlled trial. SETTING Secondary and tertiary hospitals in the Netherlands. PARTICIPANTS 168 patients with clomiphene citrate resistant polycystic ovary syndrome: 83 were allocated elec...

BACKGROUND The objective of this randomized controlled trial was to assess the effect of oral contraceptive pill (OCP) pretreatment on the probability of ongoing pregnancy in patients treated with a GnRH antagonist for IVF. METHODS A fixed dose of 200 IU recombinant FSH (rFSH) was started in 425 patients either on day 2 of the menstrual cycle (non-OCP group: n = 211) or 5 days after discontin...

BACKGROUND Pregnancy rates in women of advanced maternal age undergoing in vitro fertilization (IVF) are disappointingly low. It has been suggested that the use of preimplantation genetic screening of cleavage-stage embryos for aneuploidies may improve the effectiveness of IVF in these women. METHODS We conducted a multicenter, randomized, double-blind, controlled trial comparing three cycles...

BACKGROUND There is no doubt that luteal phase support is essential to enhance the reproductive outcome in IVF cycles. In addition to progesterone and human chorionic gonadotropin, several studies have described GnRH agonists as luteal phase support to improve implantation rate, pregnancy rate and live birth rate, whereas other studies showed dissimilar conclusions. All of these studies have be...

background: the direct effect of hcg on the human endometrium was studied several times. objective: the objectives of this study were to evaluate the effectiveness of intrauterine injection of recombinant human chorionic gonadotropin (rhcg) before embryo transfer (et). materials and methods: in this randomized placebo-controlled clinical trial, a total number of 182 infertile patients undergoin...

BACKGROUND Among subfertile women undergoing assisted reproductive technology (ART), hormone pills given before ovarian stimulation may improve outcomes. OBJECTIVES To determine whether pretreatment with the combined oral contraceptive pill (COCP) or with a progestogen or oestrogen alone in ovarian stimulation protocols affects outcomes in subfertile couples undergoing ART. SEARCH METHODS W...