The white-opaque switch is a bistable, epigenetic transition affecting multiple traits in Candida albicans including mating, immunogenicity, and niche specificity. To compare how the two cell states respond to external cues, we examined the fitness, phenotypic switching, and filamentation properties of white cells and opaque cells under 1,440 different conditions at 25°C and 37°C. We demonstrat...

Background and Aim: This study evaluated the effect of hydrothermal aging on opti-cal and mechanical properties of opaque and translucent zirconia. Materials and Methods: For the biaxial flexural strength (BFS) test, 40 sintered opaque and translucent disc-shaped zirconia, and for the assessment of surface rough-ness and optical properties, 20 specimens were fabricated and artificially aged in...

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Depending on the environmental conditions, the pathogenic yeast Candida albicans can undergo different developmental programs, which are controlled by dedicated transcription factors and upstream signaling pathways. C. albicans strains that are homozygous at the mating type locus can switch from the normal yeast form (white) to an elongated cell type (opaque), which is the mating-competent form...

The ability to switch between yeast and filamentous forms is central to Candida albicans biology. The yeast-hyphal transition is implicated in adherence, tissue invasion, biofilm formation, phagocyte escape, and pathogenesis. A second form of morphological plasticity in C. albicans involves epigenetic switching between white and opaque forms, and these two states exhibit marked differences in t...

Objectives: Metal-ceramic restorations are the standard by which all esthetic restorations are measured. Fracture of dental restorations is a multifactorial problem, which is serious and costly. Debonding of porcelain from metal substructure and the bond strength depend on many factors. The purpose of this study was to determine whether or not the opaque porcelain thickness has a significant ef...

In this paper, we propose an identities(ID) based watermarking scheme for Java programs. In our scheme, the watermark is generated by participants’ identities, embedded via the watermarked opaque predicates, and verified using zero-knowledge proof. We also present a construction of a family of opaque predicates by Legendre symbol, which is resilient, cheap, and stealthy. The order of the waterm...