Accidental intra-arterial injection as a consequence of drug misuse has been described in both the upper and lower limbs. We present a case in which a drug abuser injected heroin into his femoral artery. This resulted in necrosis of the femoral artery requiring an autologous graft. A life threatening haemorrhage necessitated ligation of the common femoral artery. His limb survived.

introduction: association between single-nucleotide polymorphisms (snps) in mu opioid receptor gene and drug addiction has been shown in various studies. here, we have evaluated the existence of polymorphisms in exon 3 of this gene in iranian population and investigated the possible association between these mutations and opioid addiction.  methods: 79 opioid-dependent subjects (55 males, 24 fe...

background in clinical practice, the level of sensory block in spinal anesthesia in opium abusers is lower than that in non-abusers because of adaptive changes caused by opium use. objectives the aim of this study was to investigate the level of sensory block resulting from the intrathecal administration of 0.5% bupivacaine in opium abuser patients undergoing lower extremity and lower abdominal...

conclusions a modified tool to assess methadone treatment response serves to identify patients at high-risk for relapse at a minimal cost, as well as evaluate the relevant physical and psycho-social domains affecting opioid-dependent patients. the great will serve as a useful adjunct to regular clinical assessments, allowing clinicians and researchers to properly assess opioid addiction patient...

The study aims to survey childhood abuse (CA) experiences among early education students in Jordan. An open-ended question was used collect data from 311 students. Data were analyzed using thematic analysis. Results revealed that all participants reported exposure during childhood, but differed the types of experienced. Participants verbal most frequently and sexual least frequently. also frequ...

background post laparoscopic cholecystectomy pain management can reduce recovery and discharge time. non-steroidal anti-inflammatory drugs and opioids are used for this purpose. objectives this randomized clinical trial evaluates the efficacy of diclofenac rectal suppository for the management of postoperative pain. patients and methods forty four patients were randomized to receive either 100 ...

Staphylococcus aureus is the most common cause of endocarditis in intravenous drug users. The organism gains access by intravenous injection or from the direct invasion of skin at injection sites. Known for its aggressiveness, the right sided endocarditis that ensues can lead to complications such as pulmonary abscesses and even death. We report the unusual case of an intravenous drug abuser, w...

Nocardia asteroides frequently causes primary lung infection with possible hematogenous dissemination to various organs, especially in patients with altered immune responses. The preponderance of pulmonary infections suggests an airborne route of contamination. We report a case of pulmonary nocardiosis in a previously healthy intravenous heroin abuser. The clinical and epidemiologic data strong...