OBJECTIVE To assess the relationship between in vivo measurements of optic disc topography and histomorphometric measurements of optic nerve fiber number in glaucoma. METHODS Both eyes of 10 monkeys (Macaca fascicularis) with laser-induced glaucoma in the right eye were studied. Optic disc topography was measured in vivo with a confocal scanning laser ophthalmoscope. Histomorphometry was perf...

This paper describes two complementary methods for computer analysis of the optic disc in glaucoma. The objective of both techniques is to detect and monitor changes in the optic disc through the use of digital image processing techniques that allow user intervention. In the first method, optic disc photographs from successive years are digitized, scaled and registered (aligned) with each other...

PURPOSE The parapapillary gamma zone has been defined as the parapapillary region without Bruch's membrane. We examined which morphologic parameters are associated with the presence and size of the parapapillary gamma zone. METHODS Using fundus photographs and spectral-domain optical coherence tomographic images of the optic nerve head in the population-based Beijing Eye Study, we determined ...

PURPOSE To investigate the effect of systemic nitric oxide synthase (NOS) inhibition on optic disc oxygen partial pressure (PO(2)) in normoxia and hypercapnia. METHODS Intervascular optic disc PO(2) was measured in 12 anesthetized minipigs by using oxygen-sensitive microelectrodes placed <50 microm from the optic disc. PO(2) was measured continuously during 10 minutes under normoxia, hyperoxi...

AIMS Progressive loss of neuroretinal rim tissue is known to occur early in glaucoma and measurement of the neuroretinal rim area is possible by magnification corrected analysis of optic disc photographs (planimetry). This study was performed to determine whether the facility to distinguish between glaucomatous and normal optic discs could be improved upon by: (a) taking into account the known ...

we evaluated the ability of spectral-domain optic coherence tomography (sd-oct) to differentiate large physiological optic disc cupping (lpc) from glaucomatous cupping in eyes with intraocular pressure (iop) within the normal range.â  we prospectively enrolled patients with glaucoma or presumed lpc. participants â had optic discs with confirmed or suspected glaucomatous damage (defined as a ver...

INTRODUCTION Melanocytoma of the optic disc is a benign lesion. OBJECTIVE To describe a case of optic disc melanocytoma CASE A 48-year old lady presented with gradual visual impairment associated with a floater. The right eye fundus examination showed a mass uniformly dark black in colour on the optic disc. The mass completely obscured the fluorescence on fluorescein angiography and was thu...

In this article, we propose a new method for localizing optic disc in retinal images. Localizing the optic disc and its center is the first step of most vessel segmentation, disease diagnostic, and retinal recognition algorithms. We use optic disc of the first four retinal images in DRIVE dataset to extract the histograms of each color component. Then, we calculate the average of histograms for...