background and aims. oral lichen planus (olp) is a common chronic mucocutaneous disease. patients with atrophic and erosive lichen planus often have symptoms of soreness and need proper treatment. the main therapy of olp has been the administration of topical or systemic corticosteroids. potent topical corticosteroids have been increasingly prescribed in the treatment of erosive lichen planus. ...

Background: Oral lichen planus is a chronic inflammatory disease with a poorly understood etiology. The role of angiogenesis in the development of different chronic inflammatory diseases is of great concern. Vascular endothelial growth factor (VEGF) is an important regulator of angiogenesis. We aimed to evaluate the serum level of VEGF in patients with oral lichen planus compared with normal in...

discussion the disappearance of olp might be due to immunosuppressive therapy following liver transplantation. further observations and studies are necessary to clarify the relationship between olp and pbc. case presentation we describe a case of oral lichen planus (olp) accompanied with pbc that resolved following liver transplantation 14 years later. this patient received immunosuppressive dr...

background & objective: lichen planus is a mucocutaneous disease which is relatively common and in 30-70% of patients, mucosal lesions can be seen and known as a precancerous lesion but its etiology is not completely understood. desmogleins i and iii are the main desmosomal transmembrane proteins. these proteins have been identified as the autoantigen of the autoimmune disease. the aim of t...

BACKGROUND Lichen planus is an inflammatory disease that affects the skin, the oral mucosa, or both. Generalized cutaneous lichen planus may pose a therapeutic challenge for clinicians if the condition persists or flares after topical or systemic corticosteroid therapy. PURPOSE Acitretin, a systemic retinoid, can be considered a potential second-line treatment for patients with generalized cu...

Background & Objective: Lichen planus is a mucocutaneous disease which is relatively common and in 30-70% of patients, mucosal lesions can be seen and known as a precancerous lesion but its etiology is not completely understood. Desmogleins I and III are the main desmosomal transmembrane proteins. These proteins have been identified as the autoantigen of the autoimmune disease. The aim...

BACKGROUND An association between HCV infection and lichen planus is uncertain because the prevalence of HCV infection in patients with lichen planus varies considerably from one geographic area to another. The purpose of this study was to determine the frequency of anti-HCV antibodies and its association with various clinical types of lichen planus in Mekkah, Saudi Arabia. METHODS A total of...

OBJECTIVE Helicobacter pylori infection is one of the most common bacterial infections in men. This gastrointestinal pathogen is closely related to gastritis, peptic ulcers, and the increased risk of gastric cancer. Numerous studies have indicated oral cavities as possible Helicobacter pylori reservoirs. Helicobacter pylori has been detected both in supragingival and subgingival plaques, and al...

Lichen planus is a chronic papulosquamous dermatoses in which both skin and mucosae are involved. There are various morphological forms of lichen planus. Hypertrophic lichen planus is one of the rare clinical variants. Herein, we report a very unusual presentation of hypertrophic lichen planus. A similar presentation has not been reported in literature yet, to the best of our knowledge.

BACKGROUND AND AIMS Oral lichen planus (OLP) is a common chronic mucocutaneous disease. Patients with atrophic and erosive lichen planus often have symptoms of soreness and need proper treatment. The main therapy of OLP has been the administration of topical or systemic corticosteroids. Potent topical corticosteroids have been increasingly prescribed in the treatment of erosive lichen planus. T...