INTRODUCTION Peptic ulcer disease is still the major cause of gastrointestinal perforation despite major improvements in both diagnostic and therapeutic strategies. While the diagnosis of a perforated ulcer is straightforward in typical cases, its clinical onset may be subtle because of comorbidities and/or concurrent therapies. CASE PRESENTATION We report the case of a 53-year-old Caucasian ...

Cytomegalovirus (CMV) is one of eight herpes virus that can cause disease in humans affecting the 30-100% of the population. In the oral cavity, CMV infection appears as a common ulcerated lesion, without clinical pathognomonic signs. The locations of oral lesions are hard palate, soft palate, tongue and floor of the mouth. This case report describes the case of a 59-year-old woman with a painf...

A 5 year old Chinese boy presented with recurrent oral ulceration followed by motor and vocal tics. The Chinese herbal spray he used for his mouth ulcers was found to have a high mercury content. His blood mercury concentration was raised. Isolated tics as the sole presentation of mercury intoxication has not previously been reported.

OBJECTIVE Some rheumatic diseases are being influenced by weather conditions. We examined the relationship between oral ulcers and weather/season in Behçet's disease (BD) patients and evaluated the oral ulcers' characteristics by the patients' perspectives. MATERIAL AND METHODS Patients with BD were evaluated using a self-questionnaire, including patients' clinical and demographical character...

OBJECTIVES The primary objective of the following study is to determine and secondary objective is to compare the efficacy and safety of 5% amlexanox oral paste in the treatment of recurrent minor aphthous ulcers and also to evaluate the recurrence rate of aphthous ulcers over a period of 1 year. MATERIALS AND METHODS The present study was conducted on 100 patients diagnosed to have recurrent...

Four patients with nicorandil induced ulceration are described, and the literature on the subject is reviewed. Nicorandil induced ulcers are very painful and distressing for patients. Clinically they appear as large, deep, persistent ulcers that have punched out edges. They are poorly responsive to topical steroids and usually require alteration of nicorandil treatment. The ulceration tends to ...

Some conditions that can mimic canker sores include traumatic injury, autoimmune conditions, viral infections (such as herpes simplex and herpes zoster [shingles]), and most importantly, oral cancer. In addition, oral ulcers can be associated with a number of systemic conditions in which the oral ulcers represent only a small part of the underlying problem. A general rule of thumb recommended b...

The aerial part of Equisetum telmateia Ehrh. is used against various conditions including stomachache and peptic ulcer in Turkish folk medicine. In order to prove the claimed anti-ulcerogenic potential of the plant, aqueous and methanol extracts were prepared from aerial parts of E. telmateia and investigated for their anti-ulcerogenic effect on ethanol-induced gastric ulcer model in rats. Phar...