نتایج جستجو برای: organelles
تعداد نتایج: 14532 فیلتر نتایج به سال:
Biochemical, pharmacological and immunocytochemical studies have implicated the microtubule-activated ATPase, kinesin, in the movement of membrane bounded organelles in fast axonal transport. In vitro studies suggested that kinesin moves organelles preferentially in the anterograde direction, but data about the function and precise localization of kinesin in the living axon were lacking. The cu...
Early Drosophila embryos are large cells containing a vast array of conventional and embryo-specific organelles. During the first three hours embryogenesis, these organelles undergo dramatic movements powered by actin-based cytoplasmic streaming motor-driven trafficking along microtubules. The development multitude small, organelle-specific fluorescent probes (FPs) makes it possible to visualiz...
Abstract Huntington’s disease (HD) is a late onset, inherited neurodegenerative disorder for which early pathogenic events remain poorly understood. Here we show that mutant exon 1 HTT proteins are recruited to subset of cytoplasmic aggregates in the cell bodies neurons brain sections from presymptomatic HD, but not wild-type, mice. This occurred stage and polyglutamine-length dependent manner....
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