This work reports on studies concerning with the interaction of important environmental contaminants, such as organotins, with model and biological systems. Organometallic compounds are synthesized and used for applications in industry and agriculture. Moreover, some organometallics can be directly formed in the environment by the action of microbial agents on inorganic precursors. Because of t...

Nuclear receptors play important roles in the maintenance of the endocrine system, regulation of organ differentiation, and fetal development. Endocrine disruptors exert their adverse effects by disrupting the endocrine system via various mechanisms. To assess the effects of endocrine disruptors on nuclear receptors, we developed a high-throughput method for identifying activators of nuclear re...

Water and surface sediment samples were analyzed for butyltins (TBT, DBT, MBT) from various ports along the east and west coast of India. The total butyltin (TB) in water samples varied between ~1.7 and 342 ng S nl⁻¹, whereas for sediments it varied between below detection limit to 14861 ng S ng⁻¹ dry weight of sediment. On an average Chennai port recorded the highest level of butyltins in the ...

A new synthetic scheme towards silica-supported organotrichlorotin derivatives has been developed. It involves the synthesis of (11-triethoxysilyl)undecyltricyclohexyltin, followed by sol-gel processing and, subsequently in the formation of the resulting hybrid silica, by electrophilic substitution of the tricyclohexyltin function by the target grafted trichlorotin using tin tetrachloride. HR-M...

Speciation, identification of the chemical states of elements in the environment, is indispensable in determining the environmental behavior, bioavailability, and the influence of elements on the quality of the environment. For speciation, X-ray absorption fine structure (XAFS) is a powerful tool, because it is a direct method by which we can avoid the change of the chemical state of target ele...

Organotin (IV) complex is part of the organometallic chemistry and in recently decades have a variety interesting application used it. A new class metallomesogens LC (A) Ph3Sn(VAL), (B) Bu3Sn(VAL), (C) Ph2Sn(VAL)2 (D) Bu2Sn(VAL)2 was synthesis through reaction valsartan ligand with (di- or tri- butyl tin chloride salt) phenyl methanol solvent. 1H NMR,119 Sn NMR, FTIR CHN elemental analyses were...