The paper shows analogies between the mechanisms of calcification arteries, various tissues and bone mineralization. In same are involved, as at ossification an organic matrix a bone, including participation stem cells. arteries capillaries organs found polypotent precursors – mesenchymal cells, presumably responsible for pathological mineralization arterial wall. Circulating in blood present i...

The expression of osteonectin (ON) in osteoarthritic articular cartilage was investigated by enzyme immunohistochemistry and colloidal gold immunoelectron microscopy. A total of 96 specimens from 9 knees of 8 patients with osteoarthritis (OA) were examined. In OA cartilage, ON-positive cells varied in distribution and were not seen in all the specimens obtained from the same patient. However, i...

UNLABELLED Bone morphogenetic protein type 2 (BMP-2) is a potent local factor, which promotes bone formation and has been used as an osteogenic supplement for mesenchymal stem cells. OBJECTIVES This study evaluated the effect of a recombinant BMP-2 as well as the endogenous BMP-4 and BMP-7 in the osteogenic differentiation of adipose-derived stem cells (ASCs) in medium supplemented with ascor...

Background: The aim of this study was to evaluate the role AT1 and AT2 receptors in a periodontal inflammation experimental model. Methods: Periodontal induced by LPS/Porphyromonas gingivalis. Maxillae, femur, vertebra were scanned using Micro-CT. Maxillae analyzed histopathologically, immunohistochemically, RT-PCR. Results: showed decreased BMD H compared with WT (p < 0.05). femur increased...

Hydroxyapatite (HA) can be coated on various materials surface and has the function of osteogenicity. Microporous silk scaffold has excellent biocompatibility. In this study, alternate soaking technology was used to coat HA on microporous silk scaffolds. However, the cell proliferation was found to decrease with the increasing thickness (cycles of soaking) of HA-coating. This study aims to dete...

Osteopontin (OP) and osteonectin (ON) are bone matrix proteins produced by mammary and other cancers. These proteins may play a role in tumor invasion and metastasis through integrin-mediated signal transduction. We evaluated expressions of OP and ON in 253 resected infiltrating ductal carcinoma of the breast, using immunohistochemical staining and follow-up data. OP and ON were detected 87.4% ...