STUDY DESIGN An Institutional Review Board-approved Phase I efficacy study of inflatable bone tamp usage in the treatment of symptomatic osteoporotic compression fractures. OBJECTIVES To evaluate the safety and efficacy of inflatable bone tamp reduction and cement augmentation, "kyphoplasty," in the treatment of painful osteoporotic vertebral compression fractures. SUMMARY OF BACKGROUND DAT...

Biomechanical tests are widely used in animal studies on osteoporotic fracture healing. However, the biomechanical recovery process is still unknown, leading to difficulty in choosing time points for biomechanical tests and in correctly assessing osteoporotic fracture healing. To determine the biomechanical recovery process during osteoporotic fracture healing, studies on osteoporotic femur fra...

STUDY DESIGN We retrospectively assessed the results of percutaneous balloon kyphoplasty (KP) by clinical and radiological methods. PURPOSE To evaluate the outcome of KP as a treatment for osteoporotic burst fractures. OVERVIEW OF LITERATURE Many surgeons are concerned about the possibility of neurological complications after percutaneous kyphoplasty for osteoporotic burst fractures, second...

BACKGROUND Treatment of distal radius fractures in patients of a younger than osteoporotic age is complex, because they often are the result of a high-energy trauma and have intra-articular fractures and associated injuries. As yet no fracture classification exists that predicts outcome. Our aim was to find the earliest possible prognostic factor by testing which radiological parameter on the t...

STUDY DESIGN Prospective cohort study. PURPOSE To prospectively investigate the influence of presence of bone marrow edema (BME) in non acute osteoporotic verterbral compression fractures on postoperative clinical outcome in patients treated by percutaneous vertebroplasty (PV). OVERVIEW OF LITERATURE Although PV is widely used to treat osteoporotic collapsed vertebral compression fractures ...

OBJECTIVE To determine whether genetic factors partly explain variation in risk of osteoporotic fracture, the true end point of the osteoporosis problem. DESIGN Prospective 25 year follow up of a nationwide cohort of elderly Finnish twins. SETTING The Finnish twin cohort and the national hospital discharge register, covering the entire 5 million population of Finland. SUBJECTS All same se...

But, some of patients complain of uncontrolled persistent chronic pain and progressive collapse of vertebral body, post-traumatic kyphosis with or without neurologic deficits. It is well known that osteoporotic fracture is also associated with significant morbidity and mortality in postmenopausal women.8-12 There was an approximate 2-fold increase in risk of death following any clinical fractur...

Vertebral fractures (VF) and sacral insufficiency fractures (SIFs) are very common in osteoporotic patients with low-back pain and are often overlooked in clinical practice. Plain radiography is usually the first examination. However, on many occasions, further evaluation with CT scan, MRI and nuclear medicine studies is necessary. Nuclear medicine examinations have important applications for t...

We report the case of a 30-year-old Japanese woman with anorexia nervosa and vertebral fractures who was treated with etidronate. She had a history of anorexia nervosa, chronic back pain, osteoporosis, and multiple vertebral fractures (morphometric fractures) that responded poorly to treatment with alfacalcidol (1 μg daily) for 1 year and was treated with cyclical etidronate (200 mg for 2 weeks...

Ca is a main component of bone and 99 % of body Ca is found in the skeleton. In addition to being of great importance for the structural properties of bone, bone Ca is the major reservoir for body Ca. Ca is essential for numerous metabolic functions, and to maintain these, serum Ca is strictly regulated. Ca balance is determined by the amount of Ca in the diet (supplements included), the effici...