AIM The aim was to compare the imaging findings of (18)F-fluorodeoxyglucose ((18)F-FDG) PET and integrated PET/CT in patients with primary, recurrent or metastatic ovarian cancer. MATERIALS AND METHODS 21 women with ovarian cancer were evaluated. All patients had a integrated PET/CT scan. Localization, infiltration and uptake intensity of [(18)F]FDG were evaluated on PET and PET/CT. The certa...

PURPOSE To investigate TAP1, TAP2, and HLA class I antigen expression in primary ovarian carcinoma lesions and to assess the clinical significance of defects in the expression of these molecules. EXPERIMENTAL DESIGN Fifty-one formalin-fixed, paraffin-embedded primary ovarian carcinoma lesions were stained with affinity-purified rabbit anti-TAP1 and anti-TAP2 antibodies and with anti-HLA class...

background: we examined epidemiological aspects of dynamic changes in incidence of ovarian cancer in women of kazakh and russian nationalities in kazakhstan. methods: the material of investigation was primary data on registered patients with malignant ovarian tumors in the whole country. the study was conducted during the period of 1999-2009. evaluation of changes in ovarian cancer incidence in...

BACKGROUND Ovary is the commonest site of neoplastic and non-neoplastic lesion, can present in childhood to postmenopausal age group and accounts for the most prevalent cause of hospital admissions. AIM This study was done to analyse the frequency of ovarian lesions their clinico-histological features in a rural set up. MATERIALS AND METHODS This is a prospective study of 145 ovarian lesion...

Abstract Adnexal masses may present as symptomatic lesions or be discovered incidentally during radiological examinations. The questions asked of radiologists are firstly, what is the nature mass and secondly, does it need to removed if so, how? Multidisciplinary discussion plan patient management aim avoid two scenarios simple resection an ovarian cancer major debulking surgery for benign dise...

AIM This pilot study investigates whether heterogeneity in focal breast lesions and surrounding tissue assessed on mammography is potentially related to cancer invasion and hormone receptor status. MATERIALS AND METHODS Texture analysis (TA) assessed the heterogeneity of focal lesions and their surrounding tissues in digitized mammograms from 11 patients randomly selected from an imaging arch...

Ovarian cancer is a disease of older women. However, the molecular mechanisms of ovarian aging and their contribution to the pathogenesis of ovarian cancer are currently unclear. mTOR signalling is a major regulator of aging as suppression of this pathway extends lifespan in model organisms. Overactive mTOR signalling is present in up to 80% of ovarian cancer samples and is associated with poor...