Background and Objective: Early diagnosis of malignant pleural mesothelioma (MPM) is the key point of its treatment. The main problem is the precise diagnosis of mesothelioma and its differentiation from metastatic lung adenocarcinoma. Mesothelioma exhibits complex immunohistochemical characteristics. The aim of this study was to study hybrid immunohistochemistry in the differe...

The incidence of lung cancer metastasizing to the duodenum is rare, and its clinical presentation still not fully understood due low frequency. It can be asymptomatic or present symptomatically in various ways. Here, we case a 63-year-old female with an unusual duodenal metastasis from pulmonary adenocarcinoma, presenting new-onset seizure complicated by fracture post-ictal fall. diagnosis anem...

Serum samples of 930 sheep were tested by ELISA to assess the prevalence of anti-Toxoplasma gondii antibodies and to identify risk factors associated with the presence of toxoplasmosis in two regions of Rio Grande do Norte (Northeast Brazil), with different climatic conditions. The overall estimated prevalence was 22.1%, with 26.3% and 17.8% positive sheep in Leste Potiguar and Central Potiguar...

The diagnosis of disseminated toxoplasmosis in a 14-year-old allogeneic bone marrow recipient with graft-versus-host disease was determined by the detection of Toxoplasma gondii tachyzoites in sputum smears. Sputum analysis is a valuable alternative in the clinical assessment of pulmonary toxoplasmosis, especially when conventional invasive techniques are not practicable.

The physiological role of endothelin-1 (ET-1) in regulation of vascular tone in the perinatal lung is controversial. Recent studies suggest that ET-1 contributes to high basal pulmonary vascular resistance in the normal fetus, but its role in the modulation of pulmonary vascular tone remains uncertain. We hypothesized that high ET-1 activity opposes the vasodilator response to some physiologica...

Pulmonary infections may be induced in experimental animals by using several exposure routes. Inhalation of microbial aerosols is often viewed as the most relevant exposure route, although the comparability of either intranasal (i.n.) or intratracheal (i.t.) inoculation to aerosol inhalation is unclear. In these studies, the infection of mice with either Streptococcus zooepidemicus or influenza...

An outbreak of leptospirosis in sheep is recorded as the first epidemic of ovine leptospirosis in Egypt. The sick animals showed typical symptoms such as fever, jaundice, red urine and abortion, with a fatal course. Acute and convalescent sera were tested for demonstration of seroconversion using the microscopic agglutination testto confirm infection. Long-acting tetracycline was successfully u...

A 67-year-old man, diagnosed as primary pulmonary adenocarcinoma by intraoperative fine-needle aspiration biopsy cytology, underwent right lower lobectomy with radical lymphadenectomy. The pathological stage was Stage IIA (pT1bN1M0, N-reason: 12L positive). After surgery, nodular shadows without intrathoracic lymph node or distant metastasis were demonstrated metachronously three times by follo...