De ovi mammalium et hominis genesi (On the Genesis of the Ovum of Mammals and of Men) is an 1827 pamphlet by Karl Ernst von Baer about the anatomical observation and description of the egg [3] (ovum [4]) of mammals, like dogs and humans [5]. The pamphlet detailed evidence for the existence of the ovum [4] at the beginning of the developmental process in mammals. Prior to von Baer's publication,...

BACKGROUND Blighted ovum is one of the most common reasons for abortion during the first three months of pregnancy. Manganese superoxide dismutase (MnSOD) is an important antioxidant enzyme in the human immune system. The gene is located on 6q25 chromosome and acts on mitochondrial matrix. In the case of mutation or inactivity of this enzyme, mitochondrial and nuclear DNA will severely be destr...

Fertilized mouse ova were injected with messenger RNA for rabbit globin. The ova were labelled with [H]leucine and the synthesized rabbit a-globin measured by immunoprecipitation. Injection of rabbit globin mRNA from 4-0 to 15-8pg/ovum resulted in the synthesis of ~1200 dpm/ovum of a-globin during an 18 h incubation. A concentration of mRNA that was translated below the maximum level of globin ...

The optimal trade-off between offspring size and number can depend on details of the mode of reproduction or development. In marine organisms, broadcast spawning is widespread, and external coats are a common feature of spawned eggs. Egg jelly coats are thought to influence several aspects of fertilization and early development, including the size of the target for sperm, fertilization efficien...