Treatment of acute venous thromboembolism (VTE) and prophylaxis of recurrent events has been investigated in the THRIVE (THRombin Inhibitor in Venous Thrombe Embolism) Treatment and the THRIVE III trial using the oral direct thrombin inhibitor ximelagatran. Alanine aminotransferase (ALAT) increased in 9.6% and 6.4% of patients in the THRIVE Treatment and THRIVE III trials, respectively. The aut...

We have analyzed the properties of low column density Lyα forest clouds (12.8 ≤ logNHI ≤ 16.0) toward 5 QSOs at different redshifts, using high signal-to-noise data from the HIRES spectrograph on the Keck I 10-m telescope. The results are used to study the evolution of these clouds in the interval 2.1 < z < 3.5. We find: 1) The differential density distribution of forest clouds, f(NHI), fits an...

BACKGROUND Limited options are available for the treatment of pain in cats. Monoclonal antibodies (mAbs) that neutralize nerve growth factor (NGF) have demonstrated analgesic capacity in rodent models, people with osteoarthritis, and dogs with degenerative joint disease. HYPOTHESIS/OBJECTIVES This study describes the design and characterization of a fully felinized anti-NGF monoclonal antibod...

OBJECTIVE To evaluate the influence of preoperative serum prostate-specific antigen (PSA) level and other clinicopathological variables on the probability of biochemical failure and clinical recurrence after radical prostatectomy (RP) for localized prostate cancer. PATIENTS AND METHODS The study was a retrospective survival analysis in 211 patients undergoing retropubic RP for clinically loca...

We present a multi-wavelength study of four high redshift blazars, S5 0014+81 (z = 3.37), CGRaBS J0225+1846 (z = 2.69), BZQ J1430+4205 (z = 4.72), and 3FGL J1656.2−3303 (z = 2.40), using the quasi-simultaneous data from Swift, NuSTAR, and Fermi-Large Area Telescope (LAT) and also the archival XMM-Newton observations. Other than 3FGL J1656.2−3303, none of the sources were known as γ-ray emitters...

The protection of women and children is one problems in the Indonesian judiciary. In decision on Case Number: 1234/Pdt.G/2018/PA.Tnk 0014/Pdt.G/2019/PTA. Bdl which has permanent legal force regarding child custody by Plaintiff. However, Defendant was reluctant did not want to implement decision. So Plaintiff must file a new lawsuit for execution previous with number: 1376/Pdt.G/2019/PA.Tnk. pro...

Background: The effects of interferon1b (IFN1b ) administration in multiple sclerosis (MS) patients have been confirmed, however, those in neuromyelitis optica (NMO) patients have not been shown. In this study, we assessed the effects of IFN1b treatment on disease exacerbation and disability progression in MS or NMO patients. Methods: We reviewed a series of 104 consecutive patients with relaps...

OBJECTIVE To compare developmental outcomes of late preterm infants (34-36 weeks' gestation) with infants born at early term (37-38 weeks' gestation) and term (39-41 weeks' gestation), from infancy through kindergarten. METHODS Sample included 1000 late preterm, 1800 early term, and 3200 term infants ascertained from the Early Childhood Longitudinal Study, Birth Cohort. Direct assessments of ...

BACKGROUND & AIMS A fast-track program is a multimodal approach for patients undergoing colonic surgery that combines stringent regimens of perioperative care (fluid restriction, optimized analgesia, forced mobilization, and early oral feeding) to reduce perioperative morbidity, hospital stay, and cost. We investigated the impact of a fast-track protocol on postoperative morbidity in patients a...