63 Introduction Bone defects attributed to serious periodontitis, trauma, and injury are commonly encountered in the fields of dentistry, craniofacial surgery, and orthopedics. Although autogenous bone grafting is still considered the gold standard for treatment, this process has several drawbacks, such as the requirement of a second surgery and the limited availability of collectable bone [1]....

In chemistry of inorganic crystals, the octacalcium phosphate (OCP) is an apatite based crystals and having a hydrated layers which used in producing needle or plate-shaped hydroxyapatite (HAP) nanocrystals. Although, prepared by dissolution precipitation reaction. These reaction led to hexagonal HAP nanocrystals formation under hydrothermal condition from OCP at 180 for 3 hours with pH solutio...

The reliability of an in vitro pyrogen test system based on proinflammatory cytokine release from human monocytic cells was assessed by comparison with a test system based on a human whole blood culture as well as with the conventional rabbit pyrogen test. The human cells used as the pyrogen indicator cells were newly selected by subcloning of a human monocytic cell line, Mono-Mac-6. The select...

Herein, we show that the enhanced osteogenecity of octacalcium phosphate (OCP) biomaterial, recently identified as an important element in hybrid organic–inorganic nanocomposites involved initial hydroxyapatite crystal expansion mammal bones, results from chemical property, stemming presence lattice strain and dislocations. Two types OCPs were synthesized by wet-chemical processing (c-OCP) abse...

Biomaterials are increasingly used for bone tissue regeneration because of their potential to overcome the morbidity caused by autologous grafts and allografts. A combination properties is required, as biocompatibility, osteoconductivity, good mechanical strength fracture toughness. In this research, a compound alumina matrix with calcium titanate phosphate proposed. Magnesium stearate was poro...