An ectopic pancreas is defined as pancreatic tissue outside its normal location, anatomically separated from the pancreas.The transcription factor pancreas/duodenum homeobox protein 1 (PDX1) involved in maintaining and functions early development, beta cell differentiation, endocrine non cells. Pancreatic subunit alpha (PTF1A) affects exocrine formation regulation of acinar identity, expressed ...

EDITORIAL SYNOPSIS Two hundred and five confirmed cases of pancreatitis have been classified. Primary calcifying pancreatitis is associated with alcoholism. Pancreatic changes are patchy and related to plugging of minute ducts. Cysts are frequent. Obstruction to the main pancreatic duct may also result in chronic pancreatitis. Acute pancreatitis and acute recurrent pancreatitis are often associ...

OBJECTIVE This study was conducted to investigate the efficacy of pancreatic drainage for pain relief in advanced pancreatic cancer. METHOD Seventy-one patients with pancreatic carcinoma were divided into two groups: dilated and non-dilated pancreatic ducts. All patients underwent endoscopic retrograde cholangiopancreatography (ERCP), endoscopic biliary stenting and pancreatic stenting. Visua...

The first endoscopic retrograde cholangiopancreatography (ERCP) was performed in 1968. It is an endoscopic technique in which a specialised sideviewing upper endoscope (duodenoscope) is guided into the second part of the duodenum. A catheter can be passed through the instrument channel to cannulate the bile and/or pancreatic ducts with the help of a bridge at the tip of the duodenoscope. The bi...

Pancreatic cancer is one of the deadliest diseases with a relatively high mortality rate. The higher rate pancreatic normally result late diagnosis. Early diagnosis and detection are quintessential to survival patients. However, at early stages extremely challenging difficult by use available biomarkers serological markers. Sometimes this could be due fact that might not responsible for signs s...

Expression of type 1 and type 2 chain carbohydrate antigens during the course of morphogenesis of human embryonic pancreas was investigated using specific monoclonal antibodies and compared with the carbohydrate antigen profiles of human pancreatic cancers. The type 2 chain antigens, such as stage-specific embryonic antigen 1 (Le(x)) and I-antigens, appeared much earlier than the type 1 chain a...

In this necropsy review of 37 cases of acute pancreatitis, evidence is presented that there are at least two different initiating mechanisms in acute necrotising pancreatitis in man. Firstly, there is primary duct inflammation, with subsequent inflammation and necrosis of the pancreatic parenchyma surrounding the excretory ducts. Included in this group are cases secondary to alcohol abuse and c...

eterotopia is the presence of tissues that are not normally found in the area. The most important of these is heterotopic or aberrant pancreatic tissue, which is a rare congenital anomaly of the gastrointestinal tract. It is usually asymptomatic and commonly encountered at autopsy or surgery in 2-10% of cases1,2 especially in the gastric antrum. Other reported locations include ileum, Meckel's ...