While most people with diabetes have type 2 disease, a non-negligible minority develops secondary diabetes. Post-pancreatitis mellitus (PPDM) is an exemplar that represents sequela of pancreatitis – the common disease exocrine pancreas. Although this has been known as clinical entity since late 19th century, early 21st century high-quality epidemiological, clinical, and translational studies fr...

OBJECTIVES To study the MRI findings of the pancreatic duct in patients with acute pancreatitis. MATERIALS AND METHODS A total of 239 patients with acute pancreatitis and 125 controls were analyzed in this study. The severity of acute pancreatitis was graded using the MR severity index (MRSI) and the Acute Physiology And Chronic Healthy Evaluation II(APACHE II) scoring systems. The number of ...

Chronic calcifying/calcific pancreatitis (CCP) is a special form of chronic pancreatitis that tends to calcify or is associated with pancreatic lithiasis. Pancreatic lithiasis refers either to true stones in the duct system of the pancreas called pancreatic calculi or to false stones due to calcification of the parenchyma. Alcoholic calcific pancreatitis (ACP) is the commonest type of chronic p...

Acute pancreatitis is a single-organ disorder that has multi-organ sequelae. As a result, it can have varied presentations. Acute pancreatitis presenting as acute limb ischemia is rare. We present a patient with acute pancreatitis presenting with bilateral lower limb ischemia. The episode of acute pancreatitis resolved but the acute lower limb ischemia precipitated as the pancreatitis progresse...

Autoimmune pancreatitis is a form of chronic pancreatitis that was first described by Sarles et al. in 1961, and later coined in 1995 by Yoshida et al. [1, 2]. Subsequently, two types of autoimmune pancreatitis have been described. Autoimmune pancreatitis type 1 fits the classic description of the disease and is associated with a lymphoplasmacytic sclerosing pancreatitis and an elevated level o...

BACKGROUND The incidence of acute pancreatitis has increased sharply in many European countries and the USA in recent years. AIM To establish trends in incidence and mortality for acute pancreatitis in Wales, UK, and to assess how incidence may be linked to factors including social deprivation, seasonal effects and alcohol consumption. METHODS Use of record linked inpatient, mortality and p...

Pancreatitis occurs when digestive enzymes are activated in the pancreas. Severe pancreatitis has a 10-30% mortality rate. No specific treatments for pancreatitis exist now. Here, we discovered that interleukin-22 (IL-22) may have therapeutic potential in treating acute and chronic pancreatitis. Wild-type and IL-22 knockout mice were equally susceptible to cerulein-induced acute and chronic pan...

Drugs are a rare cause of pancreatitis. Whereas some drugs are well known to induce an attack of pancreatitis, some people may be more prone to develop pancreatitis because of personal susceptibility. We describe a recurrent case of acute pancreatitis after administration of several drugs in a patient with intestinal inflammatory bowel disease that needed to be treated with subsequent antiinfla...

Acute allograft pancreatitis is common following simultaneous pancreas and kidney (SPK) transplantation with either bladder or enteric drainage w1,2x. Allograft pancreatitis may be caused by infection, bladder drainage problems, alcohol, drugs and diet w1x. Pancreatic allograft rejection, usually occurring in the context of renal allograft rejection, may cause a syndrome similar to acute allogr...

Hereditary pancreatitis has recently emerged as an important pancreatic disease. Although relatively rare, this genetic disorder has provided major breakthroughs in our understanding of acute and chronic pancreatitis and pancreatic cancer. Furthermore, study of this disorder promises additional insights into the pathophysiology of human pancreatitis, new strategies for developing animal models ...