This study addresses the problem of "faking bad" (malingering) of abnormal types (non paranoid schizophrenia, paranoid schizophrenia, and psychopathy) when answering the EPQ-R-S personality questionnaire and clinical scales. We tested 180 students under two conditions: “fake bad” and “sincerity”. We demonstrated that although answers to EPQ-R-S may be deliberately and specifically modified, thi...

This study describes the five-year outcomes of an assertive community treatment (ACT) program that monitored 83 acquittees found not guilty by reason of insanity (NGRI) placed on conditional release (CR) into the community. Data were collected by retrospective review of court reports and a state computer database. Five arrests and 60 hospitalizations occurred during the study period; overall, t...

BACKGROUND Huntington's disease (HD) is a dominantly inherited, neurodegenerative disorder due to expansion of a polymorphic trinucleotide repeat in the short arm of chromosome 4. Clinical manifestations consist of a triad of choreic movements, cognitive decline and psychiatric syndromes starting in the fourth to fifth decade. Psychiatric manifestations vary and may precede motor and cognitive ...

The treatment of choice for acute schizophrenia is antipsychotic drug treatment and electroconvulsive therapy (ECT) and should only be considered as an option for treatment-resistant schizophrenia, where treatment with clozapine has already proven ineffective or intolerable. The use of ECT as a maintenance treatment for patients with schizophrenia and comorbid epilepsy is uncommon as scant evid...

OBJECTIVE To investigate whether inpatients with disorganized schizophrenia are more resistant to treatment. METHOD Eighty-five inpatients were assessed at admission and at discharge for schizophrenia subtype, symptom severity, and treatment resistance criteria. RESULTS Disorganized patients were significantly more treatment-resistant than paranoid patients (60%, p = 0.001), and presented w...

Platelet MAO activity was estimated in 60 male drug free schizophrenics and 26 controls matched for age. The paranoid group had significantly lower enzyme activity than the non-paranoid group and controls. Patients with premorbid schizoid personality had significantly lower enzyme activity than patients with non-schizoid premorbid personality and controls. A significant negative correlation bet...

Previous work examining the neurobiological substrates of social cognition in healthy individuals has reported modulation of a social cognitive network such that increased activation of the amygdala, fusiform gyrus, and superior temporal sulcus are evident when individuals judge a face to be untrustworthy as compared with trustworthy. We examined whether this pattern would be present in individ...

A large correlational study took a latent-variable approach to the generality of executive control by testing the individual-differences structure of executive-attention capabilities and assessing their prediction of schizotypy, a multidimensional construct (with negative, positive, disorganized, and paranoid factors) conveying risk for schizophrenia. Although schizophrenia is convincingly link...

BACKGROUND Identification of emotional facial expression and emotional prosody (i.e. speech melody) is often impaired in schizophrenia. For facial emotion identification, a recent study suggested that the relative deficit in schizophrenia is enhanced when the presented emotion is easier to recognize. It is unclear whether this effect is specific to face processing or part of a more general emot...

Background and Objectives: This study was designed to investigate the association of the gender and subtype diagnosis with the onset age of the disease, marriage, reproductive rates in the schizophrenic inpatients. Methods: Total of 463 patients (329 males and 134 females) hospitalized with the diagnosis of schizophrenia according to DSM-IV criteria and who were between 15-65 years of age were ...