BACKGROUND Intrapleural fibrinolytics have been used successfully worldwide for the management of complicated pleural effusions and empyema. Bleeding complications are usually mentioned as rare side effects, but there is no clear information in the literature addressing the alarming outcome that might result following the use of alteplase as a fibrinolytic in the management of complicated parap...

Pleural empyema remains a significant medical problem today because of its significant morbidity, prolonged hospitalisation, and increased risk of death. The aim of this research was to share our experience in creating an animal model of pleural empyema. The model of pleural empyema appears suitable for studies on the different methods used in the treatment of empyema and in the investigation o...

Twenty-three patients with nonspecific pleuritis were studied to determine clinical outcome. After a mean follow-up period of 6 months (1 to 36 months), a diagnosis was reached in 17 patients, while 6 patients remained unknown. The causes of the nonspecific pleuritis diagnosed on initial pleural biopsy were tuberculosis (11 patients, 48%), neoplasm (2 patients, 8.7%), parapneumonic effusion (1 ...

The most common cause of empyema is a complicated parapneumonic effusion, but other foci infection may also spread to the pleural space. A man in his early 30s with history testicular mixed germ cell tumor presented week pleuritic chest pain. On admission, he was tachypneic, tachycardic, and had tested positive for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Imaging rev...

INTRODUCTION The cause of exudative pleural effusion cannot be determined in some patients. The longterm outcomes of patients with undiagnosed pleural effusion were analyzed. METHODS Patients with exudative pleural effusion whose diagnostic procedures included pleural biopsy using video-assisted thoracoscopic surgery carried out between 2008 and 2012 were evaluated retrospectively. Patients d...

Aim: To determine the sensitivity and specificity of pleural fluid ADA for the diagnosis of tuberculous pleural effusion taking the cut off value of ADA as ≥ 40 mg/dl. Methods: It was a prospective, analytical study comprised of 220 patients having pleural effusion. Sputum smear examination and sputum culture for mycobacterium tuberculosis, pleural fluid examination for protein, glucose, cell c...