BACKGROUND Recent guidelines suggest pharmacologic deep vein thrombosis (DVT) prophylaxis in all patients undergoing major surgical procedures to minimize the risk of postoperative DVT and pulmonary embolism (PE). Pharmacologic DVT prophylaxis perioperatively might increase the risk of bleeding complications. Our goal was to study the risk/benefit ratio of DVT prophylaxis in patients who underg...

UNLABELLED Intraoperative neural monitoring (IONM) during thyroid surgery has gained widespread acceptance as an adjunct to the gold standard of visual identification of the recurrent laryngeal nerve (RLN). Contrary to routine dissection of the RLN, most surgeons tend to avoid rather than routinely expose and identify the external branch of the superior laryngeal nerve (EBSLN) during thyroidect...

BACKGROUND The long-term significance of normocalcemic parathormone elevation (NPE) after successful parathyroidectomy for sporadic primary hyperparathyroidism remains unclear. METHOD Of 239 consecutive patients who underwent targeted parathyroidectomy with intraoperative parathormone monitoring, 96 were followed for ≥ 10 years. NPE was defined as a normal serum calcium level and parathormone...

OBJECTIVE To examine the feasibility of minimally invasive/focused parathyroidectomy in patients with primary hyperparathyroidism and negative results on preoperative sestamibi scanning. DESIGN Retrospective review. SETTING Hospital. PATIENTS A total of 452 patients with primary hyperparathyroidism underwent parathyroidectomy between January 2005 and December 2009. MAIN OUTCOME MEASURES...

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Abstract Few cases of uraemic tumoral calcinosis (UTC) have been reported. This study aimed to investigate the clinical efficacy parathyroidectomy for UTC. Historical data patients with end-stage renal disease and UTC who underwent were analysed. Absorption metastatic calcification was compared before after operation. Changes in intact parathyroid hormone, serum calcium, phosphorus, alkaline ph...

Neonatal severe primary hyperparathyroidism presents in the first days of life with severe life-threatening hypercalcemia. It is associated with an inactivating homozygous mutation of the calcium sensing receptor gene. Total parathyroidectomy is the treatment of choice, so the surgeon must identify all the parathyroid tissue, including supernumerary and ectopic glands. We present the case of an...

HYPOTHESIS Total parathyroidectomy without autotransplantation in kidney transplant recipients leads to reduced recurrence rates and similar improvement of clinical symptoms compared with subtotal parathyroidectomy. DESIGN A retrospective cohort study. SETTING University clinic. PATIENTS Thirty-three patients with functioning renal grafts who underwent primary total (n = 17; group 1) or s...

BACKGROUND In patients with hyperparathyroidism, parathyroidectomy is the only curative therapy. Anaesthetic management differs function of etiology (primary vs. secondary or tertiary hyperparathyroidism) and surgical technique (minimally invasive or classic parathyroidectomy). OBJECTIVES To evaluate peri-operative management (focusing on hemodynamic changes, cardiac arrhythmias and patients'...

BACKGROUND In chronic hemodialysis patients with secondary hyperparathyroidism, pathological modifications of bone and mineral metabolism increase the risk of cardiovascular morbidity and mortality. Parathyroidectomy, reducing the incidence of cardiovascular events, may improve outcomes; however, its effects on long-term survival are still subject of active research. METHODS From January 2004...