Three cases are described of end stage chronic intestinal pseudo-obstruction successfully treated by subtotal enterectomy and home parenteral nutrition (HPN). In all three patients prior use of drugs to stimulate gastrointestinal motility, antibiotics to suppress bacterial overgrowth and surgical bypass of dilated bowel had failed to alleviate the symptoms of chronic intestinal obstruction. Sim...

Methods We collected retrospective data from 50 consecutive intensive care patients from July to November 2014. The inclusion criterion was patient’s receiving ≥7 days of prescribed enteral/parenteral feed. Data collected included; patient demographics, type and amount of feed given and total propofol administered in the same period. 3 patients were excluded due to no weight recorded. We calcul...

BACKGROUND Perioperative nutrition in patients with limited liver function after partial hepatic resection is still controversial. In particular, the significance of perioperative total enteral nutrition remains unresolved. The aim of this review is to investigate the impact of early postoperative total enteral nutrition on convalescence after partial liver resection. MATERIALS AND METHODS In...

Total parenteral nutrition (TPN) is an essential means of maintaining nutrition in those who are unable to do so via an enteral route. However, long term TPN can pose potentially serious complications, in particular liver related damage. This article describes a case of abnormal liver function following total parenteral nutrition and discusses the methods of potentially reducing such complicati...

BACKGROUND The difference in outcomes in patients is unclear when 2 types of enteral nutrition, ie, tube feeding and conventional oral diets with intravenous dextrose (standard care), are compared with parenteral nutrition. OBJECTIVE We reviewed systematically and aggregated statistically the results of prospective randomized clinical trials (PRCTs) to examine the relations among the nutritio...

INTRODUCTION Whether parenteral nutrition benefits growth of very low birth weight (VLBW) preterm infants in the setting of rapid enteral feeding advancement is unclear. Our aim was to examine this issue using data from Japan, where enteral feeding typically advances at a rapid rate. METHODS We studied 4005 hospitalized VLBW, very preterm (23-32 weeks' gestation) infants who reached full ente...

Paclitaxel, an anti-microtubule chemotherapeutic agent, is known for hypersensitivity reactions. Hypersensitivity reactions associated with paclitaxel may be secondary to its vehicle, Cremophor EL rather than the paclitaxel itself. In contrast, hypersensitivity reactions to parenteral nutrition are uncommon. Both the lipid component and multivitamin have been implicated in hypersensitivity reac...

Although recruited neutrophils function as first-line defense to remove bacteria, delayed apoptosis is implicated in persistent inflammation leading to organ injury. Leukotrien B4, n-6 polyunsaturated fatty acids (PUFAs) product, is one of the mediators that delay neutrophil apoptosis. The mechanism of the beneficial effects of supplementation of fish oil-based long-chain n-3 PUFAs in parentera...

CONTEXT The use of parenteral nutrition via a central venous catheter is a common practice in the neonatal intensive care setting. Extravasation of the infusate leading to an acute abdomen is a complication that has only rarely been documented. This report describes the case of a premature infant with a femoral catheter placed in the inferior vena cava, who developed an acute abdomen as a resul...

Fifty nine infants of birthweight less than 1500 g were allocated alternately to initial total parenteral nutrition or to transpyloric feeding. Mortality was similar between the two groups. Ten of the 29 infants in the transpyloric group failed to establish full enteral nutrition during the first week of life. No beneficial effects on growth were shown in infants receiving parenteral nutrition....