The hindlimb-suspended rat was used as animal model to investigate the effects induced by immobilization of the skeletal muscle in the expression of the genes encoding hepatic lipogenic enzymes. Following a 14-day period of immobilization, rats were injected intraperitoneally with radioactive acetate, and the labeling of hepatic lipids and cholesterol was evaluated 15 min after the isotope inje...

OBJECTIVE To examine the effect of the posture of immobilization upon the tensile properties in injured Achilles tendon of rat for an initial period of immobilization. METHODS Forty-two Sprague-Dawley rats were used in the present study. Eighteen rats received a total tenotomy of the right Achilles tendon to mimic total rupture and were divided into three groups comprising of 6 rats each. Ank...

Neurophysiological studies have shown that serotonergic ligands that bind to 5-HT1A, 5-HT7, and 5-HT4 serotonin receptors in brain stem have beneficial effects on respiratory neurons during opioid-induced respiratory depression. The effect of these ligands on respiratory function and pulmonary performance has not been studied. We therefore examined the effects of 8-hydroxy-2-(di-n-propylamino)t...

Antibody immobilization strategies (random, covalent, orientated and combinations of each) were examined to determine their performance in a surface plasmon resonance-based immunoassay using human fetuin A (HFA) as the model antigen system. The random antibody immobilization strategy selected was based on passive adsorption of anti-HFA antibody on 3-aminopropyltriethoxysilane (APTES)-functional...

This paper describes the immobilization of the neutral protease from Bacillus subtilis and its application in the regioselective hydrolysis of acetylated nucleosides, including building blocks useful for the preparation of anticancer products. Regarding the immobilization study, different results have been obtained depending on the immobilization procedure. Epoxy hydrophobic carriers gave a poo...

This work reports, immobilization the Cobaloxime [Co (DH) Cl;DH,dimethylglyoximato)] onto the MCM- .The surface of MCM- was initially functionalized with -aminopropyltrimethoxysilane and -pyridine. For the electrostatic immobilization this was reacted with Cobaloxime and immobilization was achieved by an electrostatic interaction between the Co Cobaloxime and the N of the pyridine and NH amine....

Contractures — limitation of passive movements in the joint are a fairly frequent complication after immobilization or mobility and loading limb due to injuries, but exact cause their formation has not been clarified. Objective. Based on meta-analysis results experimental modeling clinical studies contractures, create conceptual model formation. Methods. Literature sources from scientific bases...