‘Fuyu’ perisimmon fruit were treated with 500 nL L 1-methylcyclopropene (1-MCP) for 24 h at 20 8C and then stored at 4 8C for 45 days to investigate the effects of 1-MCP on chilling injury (CI) during storage at 4 8C. Persimmon fruit developed CI, manifested as rapid softening and external and internal browning. Injury symptoms were reduced by 1-MCP treatment. 1-MCP also delayed increases in re...

Current malaria research is geared toward identifying novel targets for malaria chemotherapy because of the growing resistance of Plasmodium falciparum to existing drug options (Trager et. al., 1997). Potential targets not yet explored are the new permeability pathways induced by Plasmodium on host erythrocytes. These pathways confer increased permeability to inorganic ions including chloride, ...

Ca signaling plays an important role in endothelial cell (EC) functions including the regulation of barrier integrity. Recently, the endogenous lipid derivative, sphingosine-1-phosphate (S1P), has emerged as an important modulator of EC barrier function. We investigated the role of endogenously generated S1P in Ca metabolism and barrier function in human umbilical endothelial cells (HUVECs) sti...

The application of membranes in various industries is one of the most urgent needs to reduce energy consumption and environmental pollutants as well as low investment costs in the process of separation. In this investigation, the optimization of effective parameters for separation of gas mixture of CH4, CO2, O2 and N2 is studied by modified poly(4-met...

We thank Ciccolini et al. (1) for their interest in our report (2) on a clinical study, published recently in PNAS. In that paper, we report that improved tumor vascular function after anti-VEGF therapy with carboplatin and nab-paclitaxel associates with survival in non-small cell lung cancer (NSCLC) patients. We also suggest that imaging and circulating markers of vascular normalization could ...