نتایج جستجو برای: pathogenicity island

تعداد نتایج: 72467  

Journal: :Proceedings of the National Academy of Sciences 2004

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Journal: :FEMS Microbiology Letters 1999

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Journal: :Infection and Immunity 2001

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Journal: :Journal of Bacteriology 2005

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Journal: :Clinical Microbiology and Infection 2006

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Journal: :Applied and Environmental Microbiology 2006

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Journal: :Journal of Bacteriology 2003

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Journal: :eLife 2017

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Journal: :Journal of bacteriology 2004
Francis E Nano Na Zhang Siobhán C Cowley Karl E Klose Karen K M Cheung Michael J Roberts Jagjit S Ludu Gregg W Letendre Anda I Meierovics Gwen Stephens Karen L Elkins

Francisella tularensis is a gram-negative, facultative intracellular pathogen that causes the highly infectious zoonotic disease tularemia. We have discovered a ca. 30-kb pathogenicity island of F. tularensis (FPI) that includes four large open reading frames (ORFs) of 2.5 to 3.9 kb and 13 ORFs of 1.5 kb or smaller. Previously, two small genes located near the center of the FPI were shown to be...

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Journal: :Proceedings of the National Academy of Sciences of the United States of America 2004
Wanyin Deng José L Puente Samantha Gruenheid Yuling Li Bruce A Vallance Alejandra Vázquez Jeannette Barba J Antonio Ibarra Paul O'Donnell Pavel Metalnikov Keith Ashman Sansan Lee David Goode Tony Pawson B Brett Finlay

Bacterial pathogenicity islands (PAI) often encode both effector molecules responsible for disease and secretion systems that deliver these effectors to host cells. Human enterohemorrhagic Escherichia coli (EHEC), enteropathogenic E. coli, and the mouse pathogen Citrobacter rodentium (CR) possess the locus of enterocyte effacement (LEE) PAI. We systematically mutagenized all 41 CR LEE genes and...

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