BACKGROUND Myopia has become a significant global public health concern, and is highly prevalent worldwide especially in Asian countries. It is associated with genetic factors as well as socioeconomic status; however, the underlying cause for school myopia has not been established. This study evaluates the impact of living environment on school myopia in Chinese school-aged children. METHODS ...

Myopic choroidal neovascularization (CNV) is a sight-threatening condition which occurs in eyes with myopia, particularly in those with pathologic myopia. It is the most common cause of CNV among patients younger than 50 years. Hemorrhage and exudation from the CNV lesion may eventually result in scarring or chorioretinal atrophy. While myopic CNV was previously treated with focal laser photoco...

Purpose To investigate the potential role of ranibizumab treatment on the development or enlargement of chorioretinal atrophy (CRA) at the posterior pole in eyes with myopic choroidal neovascularization (mCNV). Methods This observational case series included patients having high myopia spherical equivalent refractive error ≥ -6.00 diopters, axial length (AxL) ≥ 26.0 mm in both eyes, and mCNV ...

Pathologic myopia is defined as myopic refractive error greater than ‐6.00 diopters (D).[1] Axial myopia progression results in stretching of ocular layers which may be imaged by optical coherence tomography (OCT). These findings consist of dehiscence of retinal layers, retinal cysts, intrachoroidal cavitation, macular holes, posterior retinal detachment and choroidal neovascular membranes.[2] ...

PURPOSE To compare the aqueous humor levels of vascular endothelial growth factor (VEGF) and pigment epithelium-derived factor (PEDF) in high myopic eyes and control eyes. METHODS Aqueous humor samples were collected from 21 highly myopic eyes of 20 patients (high myopia group) and from 30 cataract eyes of 30 patients with no choroidal neovascularization (CNV) or other ocular or systemic dise...

PURPOSE To identify whether myopia was associated with the visual field (VF) progression of primary open-angle glaucoma (POAG). METHODS A total of 270 eyes of 270 POAG followed up for more than 3 years with ≥9 reliable VFs by Octopus perimetry were retrospectively reviewed. Myopia was divided into: mild myopia (-2.99 diopter [D], 0), moderate myopia (-5.99, 3.00 D), marked myopia (-9.00, -6.0...

Background and purpose: A likely explanation for the increase in lens fluorescence with aging and the acceleration of this process in patients with diabetes, is that lens proteins are altered by non-enzymatic glycosylation and the further steps of the Maillard reaction. Thus, the lens fluorescence intensity appears to represent a cumulative index of glycemia over the entire lifetime of the subj...